Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections.
Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic …

Abstract The WHO Model List of Essential Medicines (EML) prioritizes medicines that have
significant global public health value. The EML can also deliver important messages on …

Abstract The French Society of Anesthesia and Intensive Care Medicine and the French
Society of Intensive Care edited guidelines focused on hospital-acquired pneumonia (HAP) …

Septicaemia likely results in high case-fatality rates in the present multidrug-resistant (MDR)
era. Amongst them are hospital-acquired pneumonia (HAP) and ventilator-associated …

Ventilator-associated pneumonia (VAP) is the most frequent life-threatening nosocomial
infection in intensive care units. The diagnostic is difficult because radiological and clinical …

Background Treatment of ventilated pneumonia is often unsuccessful, even when patients
are treated according to established guidelines. Therefore, we aimed to investigate the …

Infections occur frequently in critically ill patients and their management can be challenging
for various reasons, including delayed diagnosis, difficulties identifying causative …

Gram-negative organisms comprise a large portion of the pathogens responsible for lower
respiratory tract infections, especially those that are nosocomially acquired, and the rate of …

Purpose Nebulized colistin (NC) is a potential therapy for ventilator-associated pneumonia
(VAP); however, the clinical efficacy and safety of NC remain unclear. This study …

A fundamental step in the successful management of sepsis and septic shock is early
empiric antimicrobial therapy. However, for this to be effective, several decisions must be …