Role of platelets and platelet receptors in cancer metastasis

M Schlesinger - Journal of hematology & oncology, 2018 - Springer
The interaction of tumor cells with platelets is a prerequisite for successful hematogenous
metastatic dissemination. Upon tumor cell arrival in the blood, tumor cells immediately …

[HTML][HTML] Emerging platelet-based drug delivery systems

M Fang, R Liu, Y Fang, D Zhang, B Kong - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Drug delivery systems are becoming increasingly utilized; however, a major challenge in
this field is the insufficient target of tissues or cells. Although efforts with engineered …

Neutrophil-derived migrasomes are an essential part of the coagulation system

D Jiang, L Jiao, Q Li, R **e, H Jia, SH Wang… - Nature cell …, 2024 - nature.com
Migrasomes are organelles that are generated by migrating cells. Here we report the key
role of neutrophil-derived migrasomes in haemostasis. We found that a large number of …

Platelet receptors

KJ Clemetson, JM Clemetson - Platelets, 2019 - Elsevier
Platelet receptors are how platelets interact with their environment in order to function. They
enable signals to pass to the platelet interior and change functional aspects of the platelet …

Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins

AL Matthews, J Szyroka, R Collier… - Biochemical Society …, 2017 - portlandpress.com
A disintegrin and metalloprotease 10 (ADAM10) is a ubiquitously expressed transmembrane
protein which is essential for embryonic development through activation of Notch proteins …

Mitochondrial mechanisms in the pathogenesis of chronic inflammatory musculoskeletal disorders

K Wu, J Shieh, L Qin, JJ Guo - Cell & Bioscience, 2024 - Springer
Chronic inflammatory musculoskeletal disorders characterized by prolonged muscle
inflammation, resulting in enduring pain and diminished functionality, pose significant …

Imaging Platelet Processes and Function—Current and Emerging Approaches for Imaging in vitro and in vivo

SJ Montague, YJ Lim, WM Lee… - Frontiers in …, 2020 - frontiersin.org
Platelets are small anucleate cells that are essential for many biological processes including
hemostasis, thrombosis, inflammation, innate immunity, tumor metastasis, and wound …

Tetraspanins as potential modulators of glutamatergic synaptic function

A Becic, J Leifeld, J Shaukat… - Frontiers in Molecular …, 2022 - frontiersin.org
Tetraspanins (Tspans) comprise a membrane protein family structurally defined by four
transmembrane domains and intracellular N and C termini that is found in almost all cell …

TSPAN9 and EMILIN1 synergistically inhibit the migration and invasion of gastric cancer cells by increasing TSPAN9 expression

Y Qi, J Lv, S Liu, L Sun, Y Wang, H Li, W Qi, W Qiu - BMC cancer, 2019 - Springer
Background Globally, the incidence and mortality rates of gastric cancer are high, and its
poor prognosis is closely related to tumor recurrence and metastasis. Therefore, the …

Emerging technologies for understanding platelet diversity

JWM Heemskerk, J West - Arteriosclerosis, Thrombosis, and …, 2022 - ahajournals.org
This review discusses our understanding of platelet diversity with implications for the roles of
platelets in hemostasis and thrombosis and identifies advanced technologies set to provide …