The association between inflammation and cancer has been pointed out in epidemiological
and clinical studies, revealing how chronic inflammation may contribute to carcinogenesis in …

The JAK-STAT signalling pathway regulates cellular processes like cell division, cell death
and immune regulation. Dysregulation has been identified in solid tumours and STAT3 …

The Hippo pathway controls several biological processes, including cell growth,
differentiation, motility, stemness, cell contact, immune cell maturation, organ size, and …

Background Constitutively activated nuclear factor kappa B (NF-κB) signalling plays vital
roles in bladder urothelial carcinoma (BC) progression. We investigate the effect of receptor …

Background: Targeting inflammatory microenvironment is a promising anti-tumor strategy.
Paeonol is a phenolic compound with effective anti-inflammatory and anti-tumor properties …

Bladder cancer is the fourth most commonly diagnosed malignancy in men worldwide and
has one of the highest recurrence rates of all cancers. This cancer type is unique because …

Signal transducer and activator of transcription 3 (STAT3) regulates the expression of genes
mediating cell survival, proliferation and angiogenesis and is aberrantly activated in various …

To date, no reported studies have explored the impacts of microcystin-LR (MC-LR) on
bladder tissues, and even the occurrence of bladder cancer. The current study explores the …

Muscle-invasive bladder cancer (MIBC) is an aggressive form of urothelial bladder
carcinoma (UBC) with poorer outcomes compared to the non-muscle invasive form (NMIBC) …

Sažetak Bladder cancer (BCa) is one of the most common urinary cancers. The present
study aims to investigate whether Paeoniflorin (Pae) can exert inhibitory effects on BCa. The …