[HTML][HTML] Potential and therapeutic roles of diosmin in human diseases
Because of their medicinal characteristics, effectiveness, and importance, plant-derived
flavonoids have been a possible subject of research for many years, particularly in the last …
flavonoids have been a possible subject of research for many years, particularly in the last …
Pharmacology of diosmin, a citrus flavone glycoside: an updated review
SH Gerges, SA Wahdan, DA Elsherbiny… - European journal of …, 2022 - Springer
Flavonoids are phytochemicals that are well known for their beneficial pharmacological
properties. Diosmin is a flavone glycoside derived from hesperidin, a flavanone abundantly …
properties. Diosmin is a flavone glycoside derived from hesperidin, a flavanone abundantly …
[HTML][HTML] Diosmin alleviates doxorubicin-induced liver injury via modulation of oxidative stress-mediated hepatic inflammation and apoptosis via NfkB and MAPK …
Hepatotoxicity caused by chemotherapeutic drugs (eg, doxorubicin) is of critical concern in
cancer therapy. This study focused on investigating the modulatory effects of diosmin …
cancer therapy. This study focused on investigating the modulatory effects of diosmin …
Emodin disrupts the Notch1/Nrf2/GPX4 antioxidant system and promotes renal cell ferroptosis
M **ng, X Ma, X Wang, H Wang, M **e… - Journal of Applied …, 2023 - Wiley Online Library
Emodin has been demonstrated to possess multiple pharmacological activities. However,
emodin has also been reported to induce nephrotoxicity at high doses and with long‐term …
emodin has also been reported to induce nephrotoxicity at high doses and with long‐term …
Diosmin mitigates gentamicin-induced nephrotoxicity in rats: Insights on miR-21 and-155 expression, Nrf2/HO-1 and p38-MAPK/NF-κB pathways
Gentamicin (GNT) is the most frequently used aminoglycoside. However, its therapeutic
efficacy is limited due to nephrotoxicity. Thus, the potential anticipatory effect of Diosmin …
efficacy is limited due to nephrotoxicity. Thus, the potential anticipatory effect of Diosmin …
Geraniol ameliorates doxorubicin-mediated kidney injury through alteration of antioxidant status, inflammation, and apoptosis: potential roles of NF-κB and Nrf2/Ho-1
Doxorubicin-mediated kidney impairment is a serious problem in cancer treatment.
Accordingly, this work investigated the ability of geraniol to modulate doxorubicin-induced …
Accordingly, this work investigated the ability of geraniol to modulate doxorubicin-induced …
Nephroprotective effect of diosmin against sodium arsenite-induced renal toxicity is mediated via attenuation of oxidative stress and inflammation in mice
Arsenic compounds, which are used in different industries like pesticide manufacturing,
cause severe toxic effects in almost all organs, including the kidneys. Since the primary …
cause severe toxic effects in almost all organs, including the kidneys. Since the primary …
Assessment of anticancer properties of cumin seed (Cuminum cyminum) against bone cancer
Introduction Early-life osteosarcoma is associated with severe morbidity and mortality,
particularly affecting young children and adults. The present cancer treatment regimen is …
particularly affecting young children and adults. The present cancer treatment regimen is …
Phosphocreatine attenuates doxorubicin-induced nephrotoxicity through inhibition of apoptosis, and restore mitochondrial function via activation of Nrf2 and PGC-1α …
Doxorubicin (DOX), a chemotherapy drug widely recognized for its efficacy in cancer
treatment, unfortunately, has significant nephrotoxic effects leading to kidney damage. This …
treatment, unfortunately, has significant nephrotoxic effects leading to kidney damage. This …
Diosmin exerts hepatoprotective and antihyperglycemic effects against sodium arsenite-induced toxicity through the modulation of oxidative stress and inflammation in …
Background Chronic exposure to high concentrations of inorganic arsenic (NaAsO 2) in
drinking water is related to an increase in the risk of liver toxicity and diabetes. Diosmin has …
drinking water is related to an increase in the risk of liver toxicity and diabetes. Diosmin has …