DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Nucleolin or C23, is one of the most abundant non-ribosomal phosphoproteins of nucleolus.
However, in several cancers, nucleolin is highly expressed both intracellularly and on the …

The non-specificity of standard anticancer therapies has profound detrimental
consequences in clinical treatment. Therapeutic specificity can be precisely achieved using …

Traditional nanoparticle carriers such as liposomes, micelles, and polymeric vehicles
improve drug delivery by protecting, stabilizing, and increasing the circulatory half-life of the …

DNA nanostructures exhibit versatile geometries and possess sophisticated capabilities not
found in other nanomaterials. They serve as customizable nanoplatforms for orchestrating …

The development of novel nanoparticle-based drug delivery systems (nano-DDSs) with high
loading capacity, low toxicity, precise targeting, and excellent biocompatibility remains …

Due to the limitations of conventional cancer treatment methods, nanomedicine has
appeared as a promising alternative, allowing improved drug targeting and decreased drug …

DNA nanostructures have shown potential in cancer therapy. However, their clinical
application is hampered by the difficulty to deliver them into cancer cells and susceptibility to …

G-quadruplex is a three-dimensional secondary structure of nucleic acids formed by the
Hoogsteen hydrogen pairing of four guanines. Diverse topologies of G-quadruplex could be …