Short-chain fatty acids: linking diet, the microbiome and immunity

ER Mann, YK Lam, HH Uhlig - Nature Reviews Immunology, 2024 - nature.com
The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial
metabolites and their availability in the gut and other organs is determined by environmental …

Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Early-life interactions between the microbiota and immune system: impact on immune system development and atopic disease

K Donald, BB Finlay - Nature Reviews Immunology, 2023 - nature.com
Prenatal and early postnatal life represent key periods of immune system development. In
addition to genetics and host biology, environment has a large and irreversible role in the …

[HTML][HTML] Postbiotics: current trends in food and pharmaceutical industry

P Thorakkattu, AC Khanashyam, K Shah, KS Babu… - Foods, 2022 - mdpi.com
Postbiotics are non-viable bacterial products or metabolic byproducts produced by probiotic
microorganisms that have biologic activity in the host. Postbiotics are functional bioactive …

Microbiome-based therapeutics

MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …

Bifidobacterium mechanisms of immune modulation and tolerance

SJ Gavzy, A Kensiski, ZL Lee, EF Mongodin, B Ma… - Gut …, 2023 - Taylor & Francis
Bifidobacterium is a widely distributed commensal bacterial genus that displays beneficial
pro-homeostatic and anti-inflammatory immunomodulatory properties. Depletion or absence …

Bifidobacterium species associated with breastfeeding produce aromatic lactic acids in the infant gut

MF Laursen, M Sakanaka, N von Burg, U Mörbe… - Nature …, 2021 - nature.com
Breastfeeding profoundly shapes the infant gut microbiota, which is critical for early life
immune development, and the gut microbiota can impact host physiology in various ways …

Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?

S Deleu, K Machiels, J Raes, K Verbeke, S Vermeire - EBioMedicine, 2021 - thelancet.com
The gut microbiome and the intestinal immune system are driving contributors to
inflammatory bowel diseases (IBD). Both have an important signalling factor in common …

Gut microbiota and immune system interactions

JY Yoo, M Groer, SVO Dutra, A Sarkar, DI McSkimming - Microorganisms, 2020 - mdpi.com
Dynamic interactions between gut microbiota and a host's innate and adaptive immune
systems are essential in maintaining intestinal homeostasis and inhibiting inflammation. Gut …

The effect of probiotics on the production of short-chain fatty acids by human intestinal microbiome

P Markowiak-Kopeć, K Śliżewska - Nutrients, 2020 - mdpi.com
The relationship between diet and the diversity and function of the intestinal microbiome and
its importance for human health is currently the subject of many studies. The type and …