Circulating tumor cell-derived preclinical models: current status and future perspectives

Z Kahounová, M Pícková, S Drápela, J Bouchal… - Cell Death & …, 2023 - nature.com
Despite the advancements made in the diagnosis and treatment of cancer, the stages
associated with metastasis remain largely incurable and represent the primary cause of …

Clinical applications of circulating tumour cells and circulating tumour DNA in non-small cell lung cancer—an update

J Kapeleris, M Ebrahimi Warkiani, A Kulasinghe… - Frontiers in …, 2022 - frontiersin.org
Despite efforts to improve earlier diagnosis of non-small cell lung cancer (NSCLC), most
patients present with advanced stage disease, which is often associated with poor survival …

Preclinical models to study patient-derived circulating tumor cells and metastasis

KN Suvilesh, Y Manjunath, K Pantel, JT Kaifi - Trends in Cancer, 2023 - cell.com
Circulating tumor cells (CTCs) that are detached from the tumor can be precursors of
metastasis. The majority of studies focus on enumeration of CTCs from patient blood to …

Short-term ex vivo culture of CTCs from advance breast cancer patients: clinical implications

N Carmona-Ule, M González-Conde, C Abuín… - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumor cells (CTCs) are responsible for metastasis, they
represent tumor biology and have also predictive value for therapy monitoring and …

Circulating tumor cells as a promising target for individualized drug susceptibility tests in cancer therapy

DJ Smit, K Pantel, M Jücker - Biochemical pharmacology, 2021 - Elsevier
Circulating tumor cells (CTCs) play a crucial role in metastasis and became an emerging
topic in today's cancer research. In addition, the analysis of CTCs in liquid biopsies will be a …

Advancements in circulating tumor cell research: bridging biology and clinical applications

P Salu, KM Reindl - Cancers, 2024 - mdpi.com
Simple Summary Cancer remains one of the leading causes of death worldwide due to
widespread metastasis. Circulating tumor cells (CTCs) were first detected in 1886 and have …

[HTML][HTML] Phenoty** neuroblastoma cells through intelligent scrutiny of stain-free biomarkers in holographic flow cytometry

D Pirone, A Montella, D Sirico, M Mugnano… - APL …, 2023 - pubs.aip.org
To efficiently tackle certain tumor types, finding new biomarkers for rapid and complete
phenoty** of cancer cells is highly demanded. This is especially the case for the most …

Detection of EGFR mutations in plasma cfDNA and paired CTCs of NSCLC patients before and after osimertinib therapy using crystal digital PCR

A Ntzifa, A Kotsakis, V Georgoulias, E Lianidou - Cancers, 2021 - mdpi.com
Simple Summary Liquid biopsy is a useful tool during longitudinal monitoring of NSCLC
patients and requires highly sensitive and reliable technologies for accurate detection of …

Cell lines of circulating tumor cells: what is known and what needs to be resolved

Y Shimada, T Sudo, S Akamatsu, T Sunada… - Journal of Personalized …, 2022 - mdpi.com
The importance of circulating tumor cells (CTC) is well recognized. However, the biological
characteristics of CTC in the bloodstream have not yet been examined in detail, due to the …

Application of circulating tumour cells to predict response to treatment in head and neck cancer

X Zhang, C Ekanayake Weeramange, BGM Hughes… - Cellular Oncology, 2022 - Springer
Background Local recurrence and metastasis remain the major causes of death in head and
neck cancer (HNC) patients. Circulating tumour cells (CTCs) are shed from primary and …