Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research

SE Fenton, A Ducatman, A Boobis… - Environmental …, 2021 - Wiley Online Library
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

Sources, occurrence and toxic effects of emerging per-and polyfluoroalkyl substances (PFAS)

Y Manojkumar, S Pilli, PV Rao, RD Tyagi - Neurotoxicology and Teratology, 2023 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) cause potential threats to biota and are
persistent and never-ending substances in the environment. Regulations and ban on legacy …

Low-temperature mineralization of perfluorocarboxylic acids

B Trang, Y Li, XS Xue, M Ateia, KN Houk, WR Dichtel - Science, 2022 - science.org
Per-and polyfluoroalkyl substances (PFAS) are persistent, bioaccumulative pollutants found
in water resources at concentrations harmful to human health. Whereas current PFAS …

In vitro activity of a panel of per-and polyfluoroalkyl substances (PFAS), fatty acids, and pharmaceuticals in peroxisome proliferator-activated receptor (PPAR) alpha …

N Evans, JM Conley, M Cardon, P Hartig… - Toxicology and applied …, 2022 - Elsevier
Data demonstrate numerous per-and polyfluoroalkyl substances (PFAS) activate
peroxisome proliferator-activated receptor alpha (PPARα), however, additional work is …

Practical application guide for the discovery of novel PFAS in environmental samples using high resolution mass spectrometry

M Strynar, J McCord, S Newton, J Washington… - Journal of Exposure …, 2023 - nature.com
Background The intersection of the topics of high-resolution mass spectrometry (HRMS) and
per-and polyfluoroalkyl substances (PFAS) bring together two disparate and complex …

Bioactivity profiling of per-and polyfluoroalkyl substances (PFAS) identifies potential toxicity pathways related to molecular structure

KA Houck, G Patlewicz, AM Richard, AJ Williams… - Toxicology, 2021 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are a broad class of hundreds of fluorinated
chemicals with environmental health concerns due to their widespread presence and …

[HTML][HTML] External and internal human exposure to PFOA and HFPOs around a mega fluorochemical industrial park, China: Differences and implications

X Feng, X Chen, Y Yang, L Yang, Y Zhu, G Shan… - Environment …, 2021 - Elsevier
Hexafluoropropylene oxide dimer and trimer acids (HFPO-DA and HFPO-TA) are used as
alternatives to legacy perfluorooctanoic acid (PFOA); however, little is known about their …

[HTML][HTML] Complete defluorination of per-and polyfluoroalkyl substances—dream or reality?

JMA Juve, B Wang, MS Wong, M Ateia, Z Wei - Current Opinion in Chemical …, 2023 - Elsevier
The consensus of removing per-and polyfluoroalkyl substances (PFAS) from the
environment is widely recognized and enlightened by the near-zero standards released …

Comparative toxicokinetics and toxicity of PFOA and its replacement GenX in the early stages of zebrafish

K Satbhai, C Vogs, J Crago - Chemosphere, 2022 - Elsevier
Per and poly-fluoroalkyl substances (PFAS) are receiving attention due to their persistence,
and potential adverse effects on environmental and human health. Efforts to reduce long …

Short-chain per-and polyfluoralkyl substances (PFAS) effects on oxidative stress biomarkers in human liver, kidney, muscle, and microglia cell lines

ME Solan, CP Koperski, S Senthilkumar… - Environmental Research, 2023 - Elsevier
Long-chain per-and polyfluoralkyl substances (PFAS) are ubiquitous contaminants
implicated in the induction of intracellular reactive oxygen species (ROS), compromising …