Metabolomics for investigating physiological and pathophysiological processes

DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

The emerging field of quantitative blood metabolomics for biomarker discovery in critical illnesses

NJ Serkova, TJ Standiford… - American journal of …, 2011 - atsjournals.org
Metabolomics, a science of systems biology, is the global assessment of endogenous
metabolites within a biologic system and represents a “snapshot” reading of gene function …

Urine metabolite analysis offers potential early diagnosis of ovarian and breast cancers

CM Slupsky, H Steed, TH Wells, K Dabbs… - Clinical cancer …, 2010 - aacrjournals.org
Purpose: Metabolomics is a new, rapidly expanding field dedicated to the global study of
metabolites in biological systems. In this article metabolomics is applied to find urinary …

1H NMR-based Metabolomic Profiling in Mice Infected with Mycobacterium tuberculosis

JH Shin, JY Yang, BY Jeon, YJ Yoon… - Journal of proteome …, 2011 - ACS Publications
Tuberculosis (TB) is one of three major infectious diseases, and the control of TB is
becoming more difficult because of the emergence of multidrug-resistant and extensively …

Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of urine

J Carrola, CM Rocha, AS Barros, AM Gil… - Journal of proteome …, 2011 - ACS Publications
In this study, 1H NMR-based metabonomics has been applied, for the first time to our
knowledge, to investigate lung cancer metabolic signatures in urine, aiming at assessing the …

Metabolomics and its application to acute lung diseases

KA Stringer, RT McKay, A Karnovsky… - Frontiers in …, 2016 - frontiersin.org
Metabolomics is a rapidly expanding field of systems biology that is gaining significant
attention in many areas of biomedical research. Also known as metabonomics, it comprises …

Corynebacterium pseudodiphtheriticum exploits Staphylococcus aureus virulence components in a novel polymicrobial defense strategy

BL Hardy, SW Dickey, RD Plaut, DP Riggins, S Stibitz… - MBio, 2019 - journals.asm.org
Commensal bacteria in the human nasal cavity are known to suppress opportunistic
pathogen colonization by competing for limited space and nutrients. It has become …

Diagnosis of Bovine Respiratory Disease in feedlot cattle using blood 1H NMR metabolomics

C Blakebrough-Hall, A Dona, MJ D'occhio… - Scientific reports, 2020 - nature.com
Current diagnosis methods for Bovine Respiratory Disease (BRD) in feedlots have a low
diagnostic accuracy. The current study aimed to search for blood biomarkers of BRD using …

The interplay between central metabolism and innate immune responses

SC Cheng, LAB Joosten, MG Netea - Cytokine & growth factor reviews, 2014 - Elsevier
A growing body of recent studies bring into light an important cross-talk between immune
response and metabolism not only at the level of the organism as a whole, but also at the …

Metabolomics and malaria biology

V Lakshmanan, KY Rhee, JP Daily - Molecular and biochemical …, 2011 - Elsevier
Metabolomics has ushered in a novel and multi-disciplinary realm in biological research. It
has provided researchers with a platform to combine powerful biochemical, statistical …