Dendritic cell migration in inflammation and immunity
J Liu, X Zhang, Y Cheng, X Cao - Cellular & molecular immunology, 2021 - nature.com
Dendritic cells (DCs) are the key link between innate immunity and adaptive immunity and
play crucial roles in both the promotion of immune defense and the maintenance of immune …
play crucial roles in both the promotion of immune defense and the maintenance of immune …
[HTML][HTML] Targeting innate immune pathways for cancer immunotherapy
LL Cao, JC Kagan - Immunity, 2023 - cell.com
The innate immune system is critical for inducing durable and protective T cell responses to
infection and has been increasingly recognized as a target for cancer immunotherapy. In this …
infection and has been increasingly recognized as a target for cancer immunotherapy. In this …
Multiomics reveals persistence of obesity-associated immune cell phenotypes in adipose tissue during weight loss and weight regain in mice
Within adipose tissue (AT), immune cells and parenchymal cells closely interact creating a
complex microenvironment. In obesity, immune cell derived inflammation contributes to …
complex microenvironment. In obesity, immune cell derived inflammation contributes to …
Tolerogenic dendritic cells for regulatory T cell induction in man
VK Raker, MP Domogalla, K Steinbrink - Frontiers in immunology, 2015 - frontiersin.org
Dendritic cells (DCs) are highly specialized professional antigen-presenting cells that
regulate immune responses, maintaining the balance between tolerance and immunity …
regulate immune responses, maintaining the balance between tolerance and immunity …
Chemoresistance and the self-maintaining tumor microenvironment
The progression of cancer is associated with alterations in the tumor microenvironment,
including changes in extracellular matrix (ECM) composition, matrix rigidity …
including changes in extracellular matrix (ECM) composition, matrix rigidity …
CC chemokine receptors and chronic inflammation—therapeutic opportunities and pharmacological challenges
Chemokines are a family of low molecular weight proteins with an essential role in leukocyte
trafficking during both homeostasis and inflammation. The CC class of chemokines consists …
trafficking during both homeostasis and inflammation. The CC class of chemokines consists …
Migration of dendritic cell subsets and their precursors
The ability of dendritic cells (DCs) to initiate and orchestrate immune responses is a
consequence of their localization within tissues and their specialized capacity for …
consequence of their localization within tissues and their specialized capacity for …
Chagas disease cardiomyopathy: immunopathology and genetics
Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America
and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop …
and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop …
Common and biased signaling pathways of the chemokine receptor CCR7 elicited by its ligands CCL19 and CCL21 in leukocytes
MA Hauser, DF Legler - Journal of Leucocyte Biology, 2016 - academic.oup.com
Chemokines are pivotal regulators of cell migration during continuous immune surveillance,
inflammation, homeostasis, and development. Chemokine binding to their 7-transmembrane …
inflammation, homeostasis, and development. Chemokine binding to their 7-transmembrane …
Regulatory dendritic cells: there is more than just immune activation
The immune system exists in a delicate equilibrium between inflammatory responses and
tolerance. This unique feature allows the immune system to recognize and respond to …
tolerance. This unique feature allows the immune system to recognize and respond to …