The cardiovascular system: mathematical modelling, numerical algorithms and clinical applications

A Quarteroni, A Manzoni, C Vergara - Acta Numerica, 2017 - cambridge.org
Mathematical and numerical modelling of the cardiovascular system is a research topic that
has attracted remarkable interest from the mathematical community because of its intrinsic …

[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics

M Fedele, R Piersanti, F Regazzoni, M Salvador… - Computer Methods in …, 2023 - Elsevier
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

A contemporary look at biomechanical models of myocardium

R Avazmohammadi, JS Soares, DS Li… - Annual review of …, 2019 - annualreviews.org
Understanding and predicting the mechanical behavior of myocardium under healthy and
pathophysiological conditions are vital to develo** novel cardiac therapies and promoting …

Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function

A Quarteroni, T Lassila, S Rossi… - Computer Methods in …, 2017 - Elsevier
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …

[HTML][HTML] The living heart project: a robust and integrative simulator for human heart function

B Baillargeon, N Rebelo, DD Fox, RL Taylor… - European Journal of …, 2014 - Elsevier
The heart is not only our most vital, but also our most complex organ: Precisely controlled by
the interplay of electrical and mechanical fields, it consists of four chambers and four valves …

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart

M Bucelli, A Zingaro, PC Africa… - … journal for numerical …, 2023 - Wiley Online Library
We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …

Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations

R Piersanti, PC Africa, M Fedele, C Vergara… - Computer Methods in …, 2021 - Elsevier
Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …

[HTML][HTML] A cardiac electromechanical model coupled with a lumped-parameter model for closed-loop blood circulation

F Regazzoni, M Salvador, PC Africa, M Fedele… - Journal of …, 2022 - Elsevier
We propose a novel mathematical and numerical model for cardiac electromechanics,
wherein biophysically detailed core models describe the different physical processes …

[書籍][B] Mathematical modelling of the human cardiovascular system: data, numerical approximation, clinical applications

A Quarteroni, A Manzoni, C Vergara - 2019 - books.google.com
Mathematical and numerical modelling of the human cardiovascular system has attracted
remarkable research interest due to its intrinsic mathematical difficulty and the increasing …

[HTML][HTML] 3D–0D closed-loop model for the simulation of cardiac biventricular electromechanics

R Piersanti, F Regazzoni, M Salvador, AF Corno… - Computer Methods in …, 2022 - Elsevier
Two crucial factors for accurate numerical simulations of cardiac electromechanics, which
are also essential to reproduce the synchronous activity of the heart, are:(i) accounting for …