Nanosensors for early cancer detection and for therapeutic drug monitoring

E Salvati, F Stellacci, S Krol - Nanomedicine, 2015 - Taylor & Francis
The use of nanotechnology for drug delivery in cancer therapy has raised high expectations.
Additionally, the use of nanomaterials in sensors to extract and detect tumor specific …

The Evaluation of Clinical Applications for the Detection of the Alzheimer's Disease Biomarker GFAP

G Ozcelikay-Akyildiz, L Karadurmus… - Critical Reviews in …, 2024 - Taylor & Francis
One of the most prevalent neurodegenerative diseases is Alzheimer's disease (AD). The
hallmarks of AD include the accumulation of amyloid plaques and neurofibrillary tangles …

[HTML][HTML] Real-time intraoperative ultrasound in brain surgery: neuronavigation and use of contrast-enhanced image fusion

M Ganau, GK Ligarotti… - Quantitative imaging in …, 2019 - ncbi.nlm.nih.gov
Point-of-care devices for intraoperative imaging represent one of the greatest adjuvant to
modern strategies for surgical planning and execution; this is particularly true in …

[HTML][HTML] Sirtuin 5 (SIRT5) suppresses tumor growth by regulating mitochondrial metabolism and synaptic remodeling in gliomas

W Tang, B Chen, GKK Leung, KM Kiang - International Journal of …, 2024 - mdpi.com
Sirtuin 5 (SIRT5) is increasingly recognized as a key regulator of cellular metabolism, which
is commonly dysregulated in cancer cells, resulting in enhanced proliferation and tumor …

Understanding the pathological basis of neurological diseases through diagnostic platforms based on innovations in biomedical engineering: new concepts and …

L Ganau, L Prisco, GKI Ligarotti, R Ambu, M Ganau - Medicines, 2018 - mdpi.com
The pace of advancement of genomics and proteomics together with the recent
understanding of the molecular basis behind rare diseases could lead in the near future to …

Pushing the boundaries of accuracy and reliability during stereotactic procedures: a prospective study on 526 biopsies comparing the frameless robotic and image …

CH Mallereau, S Chibbaro, M Ganau… - Journal of Clinical …, 2022 - Elsevier
Introduction A 12-year long, prospective, single center study was conducted, comparing two
frameless systems for brain biopsies: ROSA robotic-assisted stereotaxy and BrainLab …

Radiosurgical options in neuro-oncology: a review on current tenets and future opportunities. Part II: adjuvant radiobiological tools

M Ganau, RI Foroni, M Gerosa, GK Ricciardi… - Tumori …, 2015 - journals.sagepub.com
Stereotactic radiosurgery (SRS) is currently a well-established, minimally invasive treatment
for many primary and secondary tumors, especially deep-sited lesions for which traditional …

How nanotechnology and biomedical engineering are supporting the identification of predictive biomarkers in neuro-oncology

M Ganau, M Paris, N Syrmos, L Ganau, GKI Ligarotti… - Medicines, 2018 - mdpi.com
The field of neuro-oncology is rapidly progressing and internalizing many of the recent
discoveries coming from research conducted in basic science laboratories worldwide. This …

Current and future applications of biomedical engineering for proteomic profiling: predictive biomarkers in neuro-traumatology

M Ganau, N Syrmos, M Paris, L Ganau, GKI Ligarotti… - Medicines, 2018 - mdpi.com
This systematic review aims to summarize the impact of nanotechnology and biomedical
engineering in defining clinically meaningful predictive biomarkers in patients with traumatic …

Second cancer affecting the central nervous system: systematic literature review exploring the link between malignant Melanoma and glioblastoma

J Todeschi, G Dannhoff, S Chibbaro, F Segbedji… - World Neurosurgery, 2023 - Elsevier
Background Glioblastoma (GBM) is a malignant primary brain cancer, among the most
devastating and lethal diseases of the central nervous system. Similarly, malignant …