Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …

Programmed cell death protein-1 (PD-1) is a checkpoint receptor expressed on the surface
of various immune cells. PD-L1, the natural receptor for PD-1, is mainly expressed in tumor …

Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold
standard for tumor diagnosis due to its high level of laboratory standardization, good …

Background: Ovarian cancer (OC), a serious gynecological malignant disease, remains an
enormous challenge in early diagnosis and medical treatment. Based on the GEO and …

Liquid biopsy is a diagnostic repeatable test, which in last years has emerged as a powerful
tool for profiling cancer genomes in real-time with minimal invasiveness and tailoring …

Circulating tumor cells (CTCs) are rare tumor cells released from primary, metastatic, or
recurrent tumors in the peripheral blood of cancer patients. CTCs isolation from peripheral …

The grand challenges of ovarian cancer early diagnosis have led to an alarmingly high
mortality rate from ovarian cancer (OC) in the past half century. In vitro diagnosis (IVD) has …

Circulating tumor cells (CTCs) derived from primary tumors and/or metastatic tumors are
markers for tumor prognosis, and can also be used to monitor therapeutic efficacy and tumor …

Simple Summary The aim of this review is to evaluate the present status of the use of cell-
free DNA and its fraction of circulating tumor DNA (ctDNA) because this year July 2022, an …

Simple Summary Poly (ADP-ribose) polymerase (PARP) inhibitors have become an
essential part of the anticancer armamentarium in ovarian cancer. As maintenence therapy …