Articular cartilage (AC), a bone-to-bone protective device made of up to 80% water and
populated by only one cell type (ie chondrocyte), has limited capacity for regeneration and …

Human cartilage tissue can be categorized into three types: hyaline cartilage, elastic
cartilage and fibrocartilage. Each type of cartilage tissue possesses unique properties and …

It remains a big challenge in clinical practice to repair large-sized bone defects and many
factors limit the application of autografts and allografts, The application of exogenous …

Meniscal tears are a frequent orthopedic injury commonly managed by conservative
strategies to avoid osteoarthritis development descending from altered biomechanics …

Decellularized extracellular matrix (dECM) has emerged as a promising biomaterial in the
fields of tissue engineering and regenerative medicine due to its ability to provide specific …

Musculoskeletal engineering has been considered as a promising approach to customize
regenerated tissue (such as bone, cartilage, tendon, and ligament) via a self-healing …

Meniscus damage is a common trauma that often arises from sports injuries or menisci
tissue degeneration. Current treatment methods focus on the repair, replacement, and …

Knee menisci are structurally complex components that preserve appropriate biomechanics
of the knee. Meniscal tissue is susceptible to injury and cannot heal spontaneously from …

The knee meniscus is the cushioning fibro-cartilage tissue present in between the femoral
condyles and tibial plateau of the knee joint. It is largely avascular in nature and suffers from …

Hydrogels and bioinks obtained from gelatin (Gel) generally present poor mechanical
properties and require a series of time-consuming and stepwise chemical processes to …