Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …

Several useful animal models for parkinsonism have been developed so far. Haloperidol‐
induced catalepsy is often used as a rodent model for the study of motor impairments …

This study evaluated the synthesis of a dual series of bromo (CHB1–CHB4)-and fluoro
(CHF1–CHF4)-based α, β-unsaturated ketones and their inhibitory activities against …

Background: Excitotoxicity is a condition in which neurons are damaged/injured by the over-
activation of glutamate receptors. Excitotoxins play a crucial part in the progression of …

Along with the increase in life expectancy, a significant increase of people suffering from
neurodegenerative diseases (ND) has been noticed. The second most common ND, after …

Parkinson's disease (PD) is a complex, age‐related neurodegenerative disease that causes
neuronal loss and dysfunction over time. An imbalance of redox potential of oxidative stress …

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
loss of dopamine-producing neurons in the substantia nigra and the abnormal cytoplasmic …

Cucurbita pepo is used as a vegetable in Pakistan and its seeds are also rich in tocopherol.
Data showed the pivotal role of tocopherol in the treatment of Parkinson's disease (PD). The …

Syzygium heyneanum is a valuable source of flavonoids and phenols, known for their
antioxidant and neuroprotective properties. This research aimed to explore the potential of …

To evaluate the anti-diabetic potential of aqueous methanolic extract of Conyza bonariensis
amongst the Wistar rats. Phytochemical and High Performance Liquid Chromatography …