[HTML][HTML] Pre-clinical whole-body fluorescence imaging: Review of instruments, methods and applications

F Leblond, SC Davis, PA Valdés, BW Pogue - Journal of photochemistry …, 2010 - Elsevier
Fluorescence sampling of cellular function is widely used in all aspects of biology, allowing
the visualization of cellular and sub-cellular biological processes with spatial resolutions in …

Small animal fluorescence and bioluminescence tomography: a review of approaches, algorithms and technology update

C Darne, Y Lu, EM Sevick-Muraca - Physics in Medicine & …, 2013 - iopscience.iop.org
Emerging fluorescence and bioluminescence tomography approaches have several
common, yet several distinct features from established emission tomographies of PET and …

Latest advances in molecular imaging instrumentation

BJ Pichler, HF Wehrl… - Journal of Nuclear …, 2008 - Soc Nuclear Med
This review concentrates on the latest advances in molecular imaging technology, including
PET, MRI, and optical imaging. In PET, significant improvements in tumor detection and …

Fluorescence molecular tomography: principles and potential for pharmaceutical research

F Stuker, J Ripoll, M Rudin - Pharmaceutics, 2011 - mdpi.com
Fluorescence microscopic imaging is widely used in biomedical research to study molecular
and cellular processes in cell culture or tissue samples. This is motivated by the high …

Multispectral optoacoustic tomography (MSOT) scanner for whole-body small animal imaging

R Ma, A Taruttis, V Ntziachristos, D Razansky - Optics express, 2009 - opg.optica.org
A major difficulty arising from whole-body optoacoustic imaging is the long acquisition times
associated with recording signals from multiple spatial projections. The acquired signals are …

Magnetic resonance–coupled fluorescence tomography scanner for molecular imaging of tissue

SC Davis, BW Pogue, R Springett, C Leussler… - Review of Scientific …, 2008 - pubs.aip.org
A multichannel spectrally resolved optical tomography system to image molecular targets in
small animals from within a clinical MRI is described. Long source/detector fibers operate in …

Hybrid system for simultaneous fluorescence and x-ray computed tomography

RB Schulz, A Ale, A Sarantopoulos… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
A hybrid imaging system for simultaneous fluorescence tomography and X-ray computed
tomography (XCT) of small animals has been developed and presented. The system …

In vivo optical imaging and dynamic contrast methods for biomedical research

EMC Hillman, CB Amoozegar… - … of the Royal …, 2011 - royalsocietypublishing.org
This paper provides an overview of optical imaging methods commonly applied to basic
research applications. Optical imaging is well suited for non-clinical use, since it can exploit …

Hybrid FMT–CT imaging of amyloid-β plaques in a murine Alzheimer's disease model

D Hyde, R de Kleine, SA MacLaurin, E Miller… - Neuroimage, 2009 - Elsevier
The need to study molecular and functional parameters of Alzheimer's disease progression
in animal models has led to the development of disease-specific fluorescent markers …

Deep-tissue reporter-gene imaging with fluorescence and optoacoustic tomography: a performance overview

NC Deliolanis, A Ale, S Morscher, NC Burton… - Molecular imaging and …, 2014 - Springer
Purpose A primary enabling feature of near-infrared fluorescent proteins (FPs) and
fluorescent probes is the ability to visualize deeper in tissues than in the visible. The …