Leishmaniasis diagnosis: an update on the use of parasitological, immunological and molecular methods

S Thakur, J Joshi, S Kaur - Journal of Parasitic Diseases, 2020 - Springer
Diagnosis of leishmaniasis has always been a major challenge as its clinical features
resemble some other commonly occurring diseases such as tuberculosis, typhoid, and …

Searching for drugs for Chagas disease, leishmaniasis and schistosomiasis: a review

SS Santos, RV de Araújo, J Giarolla, O El Seoud… - International journal of …, 2020 - Elsevier
Chagas disease, leishmaniasis and schistosomiasis are neglected diseases (NDs) and are
a considerable global challenge. Despite the huge number of people infected, NDs do not …

[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

EK Elmahallawy, AAM Alkhaldi, AA Saleh - Biomedicine & …, 2021 - Elsevier
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

Leishmania species: A narrative review on surface proteins with structural aspects involved in host–pathogen interaction

RS Kaushal, N Naik, M Prajapati… - Chemical Biology & …, 2023 - Wiley Online Library
In tropical and subtropical regions of the world, leishmaniasis is endemic and causes a
range of clinical symptoms in people, from severe tegumentary forms (such as cutaneous …

New antileishmanial quinoline linked isatin derivatives targeting DHFR-TS and PTR1: Design, synthesis, and molecular modeling studies

A Sabt, WM Eldehna, TM Ibrahim, AA Bekhit… - European Journal of …, 2023 - Elsevier
In a search for new drug candidates for one of the neglected tropical diseases,
leishmaniasis, twenty quinoline-isatin hybrids were synthesized and tested for their in vitro …

Antitrypanosomal and Antileishmanial Activity of Chalcones and Flavanones from Polygonum salicifolium

AM Zheoat, S Alenezi, EK Elmahallawy, MA Ungogo… - Pathogens, 2021 - mdpi.com
Trypanosomiasis and leishmaniasis are a group of neglected parasitic diseases caused by
several species of parasites belonging to the family Trypansomatida. The present study …

In vitro-in silico pharmacology and chemistry of Stercularin, isolated from Sterculia diversifolia

I Ahmad, F Rabbi, A Nisar, Z Ul-Haq, A Khan - Computational Biology and …, 2024 - Elsevier
Stercularin is a coumarin, isolated from the ethyl acetate fraction of stem bark and leaves of
S. diversifolia. Pharmacologically it is active against cancer, diabetes, and inflammation etc …

Insights into Leishmania Molecules and Their Potential Contribution to the Virulence of the Parasite

EK Elmahallawy, AAM Alkhaldi - Veterinary Sciences, 2021 - mdpi.com
Neglected parasitic diseases affect millions of people worldwide, resulting in high morbidity
and mortality. Among other parasitic diseases, leishmaniasis remains an important public …

Insights into the current status of privileged N-heterocycles as antileishmanial agents

N Razzaghi-Asl, S Sepehri, A Ebadi, P Karami… - Molecular …, 2020 - Springer
Leishmania, one of the most important neglected tropical diseases, is endemic in several
regions of the world and hence regarded as a serious threat to public health. Major …

Antileishmanial effect of new indeno-1, 5-naphthyridines, selective inhibitors of Leishmania infantum type IB DNA topoisomerase

A Tejeria, Y Perez-Pertejo, RM Reguera… - European Journal of …, 2016 - Elsevier
Visceral leishmaniasis is a neglected disease of poor and develo** countries. The current
therapeutic approach is based on pentavalent antimonial (Sb V) drugs and amphotericin B …