Vaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics

ZS Guo, B Lu, Z Guo, E Giehl, M Feist, E Dai… - … for immunotherapy of …, 2019 - Springer
Cancer vaccines and oncolytic immunotherapy are promising treatment strategies with
potential to provide greater clinical benefit to patients with advanced-stage cancer. In …

Tumor heterogeneity: a great barrier in the age of cancer immunotherapy

N El-Sayes, A Vito, K Mossman - Cancers, 2021 - mdpi.com
Simple Summary Despite great advances in cancer therapy, tumor heterogeneity continues
to be a great barrier for the successful treatment of cancer. It has long been established that …

A candidate multi-epitope vaccine against SARS-CoV-2

T Kar, U Narsaria, S Basak, D Deb, F Castiglione… - Scientific reports, 2020 - nature.com
In the past two decades, 7 coronaviruses have infected the human population, with two
major outbreaks caused by SARS-CoV and MERS-CoV in the year 2002 and 2012 …

Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches

R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …

Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection

M Ali, RK Pandey, N Khatoon, A Narula, A Mishra… - Scientific reports, 2017 - nature.com
Dengue is considered as a major health issue which causes a number of deaths worldwide
each year; tropical countries are majorly affected by dengue outbreaks. It is considered as …

An mRNA-based T-cell-inducing antigen strengthens COVID-19 vaccine against SARS-CoV-2 variants

W Tai, S Feng, B Chai, S Lu, G Zhao, D Chen… - Nature …, 2023 - nature.com
Herd immunity achieved through mass vaccination is an effective approach to prevent
contagious diseases. Nonetheless, emerging SARS-CoV-2 variants with frequent mutations …

Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target

RCO Sanches, S Tiwari, LCG Ferreira… - Frontiers in …, 2021 - frontiersin.org
Schistosomiasis remains a serious health issue nowadays for an estimated one billion
people in 79 countries around the world. Great efforts have been made to identify good …

Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches

A Safavi, A Kefayat, E Mahdevar, A Abiri… - Vaccine, 2020 - Elsevier
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …

Novel Immunoinformatics Approaches to Design Multi-epitope Subunit Vaccine for Malaria by Investigating Anopheles Salivary Protein

RK Pandey, TK Bhatt, VK Prajapati - Scientific reports, 2018 - nature.com
Malaria fever has been pervasive for quite a while in tropical develo** regions causing
high morbidity and mortality. The causal organism is a protozoan parasite of genus …

Immunoinformatics analysis and in silico designing of a novel multi-epitope peptide vaccine against Staphylococcus aureus

N Hajighahramani, N Nezafat, M Eslami… - Infection, Genetics and …, 2017 - Elsevier
Staphylococcus aureus is a pathogen that causes a variety of infections in humans.
Methicillin-resistant S. aureus, which is an antibiotic-resistant form, is responsible for …