The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …

Adipose tissue exhibits remarkable plasticity with capacity to change in size and cellular
composition under physiological and pathophysiological conditions. The emergence of …

Fibroblasts, the principal cell type of connective tissue, secrete extracellular matrix
components during tissue development, homeostasis, repair and disease. Despite this …

Fibrosis, or tissue scarring, develops as a pathological deviation from the physiological
wound healing response and can occur in various organs such as the heart, lung, liver …

The extracellular matrix (ECM) is a dynamic structure that surrounds and anchors cellular
components in tissues. In addition to functioning as a structural scaffold for cellular …

Persistent hyper-inflammation is a distinguishing pathophysiological characteristic of chronic
wounds, and macrophage malfunction is considered as a major contributor thereof. In this …

The landmark discoveries of leptin and adiponectin firmly established adipose tissue as a
sophisticated and highly active endocrine organ, opening a new era of investigating adipose …

Adipose tissues display a remarkable ability to adapt to the dietary status. Here, we have
applied single-nucleus RNA-seq to map the plasticity of mouse epididymal white adipose …

Coronavirus disease‐2019 (COVID‐19), caused by the highly pathogenic severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), demonstrates high morbidity and …