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Congenital hydrocephalus: a review of recent advances in genetic etiology and molecular mechanisms
The global prevalence rate for congenital hydrocephalus (CH) is approximately one out of
every five hundred births with multifaceted predisposing factors at play. Genetic influences …
every five hundred births with multifaceted predisposing factors at play. Genetic influences …
The genetic basis of hydrocephalus: genes, pathways, mechanisms, and global impact
Hydrocephalus (HC) is a heterogenous disease characterized by alterations in
cerebrospinal fluid (CSF) dynamics that may cause increased intracranial pressure. HC is a …
cerebrospinal fluid (CSF) dynamics that may cause increased intracranial pressure. HC is a …
SWI/SNF complex connects signaling and epigenetic state in cells of nervous system
VK Chmykhalo, RV Deev, AT Tokarev… - Molecular …, 2025 - Springer
SWI/SNF protein complexes are evolutionarily conserved epigenetic regulators described in
all eukaryotes. In metameric animals, the complexes are involved in all processes occurring …
all eukaryotes. In metameric animals, the complexes are involved in all processes occurring …
Biomechanical instability of the brain–CSF interface in hydrocephalus
Hydrocephalus, characterized by progressive expansion of the CSF-filled ventricles
(ventriculomegaly), is the most common reason for brain surgery.'Communicating'(ie non …
(ventriculomegaly), is the most common reason for brain surgery.'Communicating'(ie non …
Chromatin remodeling in tissue stem cell fate determination
Tissue stem cells (TSCs), which reside in specialized tissues, constitute the major cell
sources for tissue homeostasis and regeneration, and the contribution of transcriptional or …
sources for tissue homeostasis and regeneration, and the contribution of transcriptional or …
De novo variants disrupt an LDB1-regulated transcriptional network in congenital ventriculomegaly
Congenital hydrocephalus (CH), characterized by cerebral ventriculomegaly (CV), is among
the most common and least understood pediatric neurosurgical disorders. We have …
the most common and least understood pediatric neurosurgical disorders. We have …