Emerging microRNA biomarkers for colorectal cancer diagnosis and prognosis

B Chen, Z **a, YN Deng, Y Yang… - Royal Society …, 2019 - royalsocietypublishing.org
MicroRNAs (miRNAs) are one abundant class of small, endogenous non-coding RNAs,
which regulate various biological processes by inhibiting expression of target genes …

Good or not good: Role of miR-18a in cancer biology

T Kolenda, K Guglas, M Kopczyńska… - Reports of Practical …, 2020 - journals.viamedica.pl
Abstract miR-18a is a member of primary transcript called miR-17-92a (C13orf25 or
MIR17HG) which also contains five other miRNAs: miR-17, miR-19a, miR-20a, miR-19b and …

Mex3a promotes oncogenesis through the RAP1/MAPK signaling pathway in colorectal cancer and is inhibited by hsa‐miR‐6887‐3p

H Li, J Liang, J Wang, J Han, S Li… - Cancer …, 2021 - Wiley Online Library
Abstract Background Although Mex3 RNA‐binding family member A (Mex3a) has
demonstrated an important role in multiple cancers, its role and regulatory mechanism in …

miRNA in prostate cancer: Challenges toward translation

I Abramovic, M Ulamec, A Katusic Bojanac… - …, 2020 - Taylor & Francis
Prostate cancer (PCa) represents the most commonly diagnosed neoplasm among men.
miRNAs, as biomarkers, could further improve reliability in distinguishing malignant versus …

Targeting colorectal cancer stem cells as an effective treatment for colorectal cancer

YS Ma, W Li, Y Liu, Y Shi, QL Lin… - Technology in cancer …, 2020 - journals.sagepub.com
As one of the common cancers that threaten human life, the recurrence and metastasis of
colorectal cancer seriously affect the prognosis of patients. Although new drugs and …

Silencing of miR-182 is associated with modulation of tumorigenesis through apoptosis induction in an experimental model of colorectal cancer

L Perilli, S Tessarollo, L Albertoni, M Curtarello… - BMC cancer, 2019 - Springer
Abstract Background miR-182-5p (miR-182) is an oncogenic microRNA (miRNA) found in
different tumor types and one of the most up-regulated miRNA in colorectal cancer (CRC) …

miR-18a-5p is involved in the developmental origin of prostate cancer in maternally malnourished offspring rats: A DOHaD approach

SAA Santos, LMF Portela, ACL Camargo… - International Journal of …, 2022 - mdpi.com
The Developmental Origins of Health and Disease (DOHaD) concept correlates early life
exposure to stressor conditions with the increased incidence of non-communicable chronic …

The blockade of tumoral IL1β-mediated signaling in normal colonic fibroblasts sensitizes tumor cells to chemotherapy and prevents inflammatory CAF activation

NG Díaz-Maroto, G Garcia-Vicién, G Polcaro… - International Journal of …, 2021 - mdpi.com
Heterotypic interactions between newly transformed cells and normal surrounding cells
define tumor's fate in incipient carcinomas. Once homeostasis has been lost, normal …

Decreased level of miR-1301 promotes colorectal cancer progression via activation of STAT3 pathway

F Yang, H Wang, B Yan, T Li, L Min, E Chen… - Biological …, 2021 - degruyter.com
The molecular pathogenesis of colorectal cancer (CRC) has been widely investigated in
recent years. Accumulating evidence has indicated that microRNA (miRNA) dysregulation …

[HTML][HTML] The prognostic influence of tumour budding in Western patients with stage II colorectal cancer

AL Canguçu, E Valério, RBP Peixoto… - …, 2020 - ncbi.nlm.nih.gov
Background: Tumour budding (TB) refers to loss of tumour cohesiveness and is defined as
isolated cells or a cell cluster of up to four tumour cells at the microscopic analysis. The …