Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …

Cell-substrate interactions play a crucial role in the design of better biomaterials and
integration of implants with the tissues. Adhesion is the binding process of the cells to the …

Cellular form and function emerge from complex mechanochemical systems within the
cytoplasm. Currently, no systematic strategy exists to infer large-scale physical properties of …

The stiffness and nanotopographical characteristics of the extracellular matrix (ECM)
influence numerous developmental, physiological, and pathological processes in vivo …

Cells generate mechanical stresses via the action of myosin motors on the actin
cytoskeleton. Although the molecular origin of force generation is well understood, we …

Focal adhesions (FAs) are macromolecular complexes that regulate cell adhesion and
mechanotransduction. By performing fluorescence recovery after photobleaching (FRAP) …

The interplay between the mechanical properties of cells and the forces that they produce
internally or that are externally applied to them play an important role in maintaining the …

Cortical stiffness is an important cellular property that changes during migration, adhesion
and growth. Previous atomic force microscopy (AFM) indentation measurements of cells …