Understanding the biological relationship between migraine and depression

A Viudez-Martínez, AB Torregrosa, F Navarrete… - Biomolecules, 2024‏ - mdpi.com
Migraine is a highly prevalent neurological disorder. Among the risk factors identified,
psychiatric comorbidities, such as depression, seem to play an important role in its onset …

Pick fecal microbiota transplantation to enhance therapy for major depressive disorder

Y Meng, J Sun, G Zhang - Progress in Neuro-Psychopharmacology and …, 2024‏ - Elsevier
In recent years, fecal microbiota transplantation (FMT) has emerged as a promising therapy
for major depressive disorder (MDD). The goal of the operation is to restore a healthy gut …

Association of Chronic Pain with Biomarkers of Neurodegeneration, Microglial Activation, and Inflammation in Cerebrospinal Fluid and Impaired Cognitive Function

A Sadlon, P Takousis, B Ankli… - Annals of …, 2024‏ - Wiley Online Library
Objective Debate surrounds the role of chronic pain as a risk factor for cognitive decline and
dementia. This study aimed at examining the association of chronic pain with biomarkers of …

Lipopolysaccharide, VE-cadherin, HMGB1, and HIF-1α levels are elevated in the systemic circulation in chronic migraine patients with medication overuse headache …

D Vuralli, M Ceren Akgor, H Gok Dagidir… - The Journal of …, 2024‏ - Springer
Objective Medication overuse headache (MOH) was recently shown to be associated with
leaky gut in rodents. We aimed to investigate whether chronic migraine (CM) patients with …

Unraveling the interplay of neuroinflammatory signaling between parenchymal and meningeal cells in migraine headache

T Dalkara, Z Kaya, ŞE Erdener - The Journal of Headache and Pain, 2024‏ - Springer
Background The initiation of migraine headaches and the involvement of neuroinflammatory
signaling between parenchymal and meningeal cells remain unclear. Experimental …

Brain structure and cortical activity changes of new daily persistent headache: multimodal evidence from MEG/sMRI

D Qiu, W Wang, Y Mei, H Tang, Z Yuan… - The Journal of …, 2023‏ - Springer
Background New daily persistent headache (NDPH) is a rare but debilitating primary
headache disorder that poses a significant burden on individuals and society. Despite its …

Medication overuse headache is associated with elevated lipopolysaccharide binding protein and pro-inflammatory molecules in the bloodstream

HG Dağıdır, E Topa, D Vuralli, H Bolay - The journal of headache and pain, 2023‏ - Springer
Objective Medication overuse headache (MOH) is a secondary headache that accompanies
chronic migraine. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most frequently …

PACAP38/mast-cell-specific receptor axis mediates repetitive stress-induced headache in mice

H Son, Y Zhang, J Shannonhouse, R Gomez… - The Journal of …, 2024‏ - Springer
Background Pain, an evolutionarily conserved warning system, lets us recognize threats and
motivates us to adapt to those threats. Headache pain from migraine affects approximately …

Mechanism of NO2-induced migraine in rats: The exploration of the role of miR-653-3p/IGF1 axis

S Ye, L Wei, Y Jiang, Y Yuan, Y Zeng, L Zhu… - Journal of Hazardous …, 2024‏ - Elsevier
Migraine is a severely disabling primary neurological disorder. Although some studies have
confirmed that nitrogen dioxide (NO 2) pollution increases the risk of migraine, and our …

Multiomic‐based immune response profiling in migraine, vestibular migraine and Meniere's disease

P Cruz‐Granados, L Frejo, P Perez‐Carpena… - …, 2024‏ - Wiley Online Library
Migraine (MI) is the most common neurological disease, affecting with 20% of the world
population. A subset of 25% of MI patients showcase concurrent vestibular symptoms, which …