Plasmodium—a brief introduction to the parasites causing human malaria and their basic biology
S Sato - Journal of physiological anthropology, 2021 - Springer
Malaria is one of the most devastating infectious diseases of humans. It is problematic
clinically and economically as it prevails in poorer countries and regions, strongly hindering …
clinically and economically as it prevails in poorer countries and regions, strongly hindering …
Advances and opportunities in malaria population genomics
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …
Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness
The emergence of mutant K13-mediated artemisinin (ART) resistance in Plasmodium
falciparum malaria parasites has led to widespread treatment failures across Southeast …
falciparum malaria parasites has led to widespread treatment failures across Southeast …
Antimalarial drug resistance and novel targets for antimalarial drug discovery
MA Shibeshi, ZD Kifle, SA Atnafie - Infection and drug resistance, 2020 - Taylor & Francis
Malaria is among the most devastating and widespread tropical parasitic diseases in which
most prevalent in develo** countries. Antimalarial drug resistance is the ability of a …
most prevalent in develo** countries. Antimalarial drug resistance is the ability of a …
Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival
The emergence and spread of artemisinin resistance, driven by mutations in Plasmodium
falciparum K13, has compromised antimalarial efficacy and threatens the global malaria …
falciparum K13, has compromised antimalarial efficacy and threatens the global malaria …
Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa
Malaria, mostly due to Plasmodium falciparum infection in Africa, remains one of the most
important infectious diseases in the world. Standard treatment for uncomplicated P …
important infectious diseases in the world. Standard treatment for uncomplicated P …
A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites
J Birnbaum, S Scharf, S Schmidt, E Jonscher… - Science, 2020 - science.org
Artemisinin and its derivatives (ARTs) are the frontline drugs against malaria, but resistance
is jeopardizing their effectiveness. ART resistance is mediated by mutations in the parasite's …
is jeopardizing their effectiveness. ART resistance is mediated by mutations in the parasite's …
Assessing risks of Plasmodium falciparum resistance to select next-generation antimalarials
M Duffey, B Blasco, JN Burrows, TNC Wells… - Trends in …, 2021 - cell.com
Strategies to counteract or prevent emerging drug resistance are crucial for the design of
next-generation antimalarials. In the past, resistant parasites were generally identified …
next-generation antimalarials. In the past, resistant parasites were generally identified …
Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19
Abstract Chloroquine (CQ) and Hydroxychloroquine (HCQ) have been commonly used for
the treatment and prevention of malaria, and the treatment of autoimmune diseases for …
the treatment and prevention of malaria, and the treatment of autoimmune diseases for …
[HTML][HTML] Plasmodium falciparum resistance to ACTs: Emergence, mechanisms, and outlook
Emergence and spread of resistance in Plasmodium falciparum to the frontline treatment
artemisinin-based combination therapies (ACTs) in the epicenter of multidrug resistance of …
artemisinin-based combination therapies (ACTs) in the epicenter of multidrug resistance of …