Bioconversion of renewable lignocellulosics to produce liquid fuels and chemicals is one of
the most effective ways to solve the problem of fossil resource shortage, energy security, and …

Cancer stem cells (CSCs) are subpopulation of cells which have been demonstrated in a
variety of cancer models and involved in cancer initiation, progression, and development …

Few proteins have come under such intense scrutiny as superoxide dismutase-1 (SOD1).
For almost a century, scientists have dissected its form, function and then later its …

Mutations in the gene encoding Cu/Zn superoxide dismutase-1 cause amyotrophic lateral
sclerosis. Superoxide dismutase-1 mutations decrease protein stability and promote …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease in which the
motor neuron circuitry displays progressive degeneration, affecting mostly the motor …

Biotransformations are reactions mediated by microorganisms, such as fungi. These
bioreactions have high chemo-and stereoselectivity on organic substrates and can be …

Cu/Zn superoxide dismutase‐1 (SOD 1) mutations are causative for a subset of amyotrophic
lateral sclerosis (ALS) cases. These mutations lead to structural instability, aggregation and …

Chagas disease is a neglected tropical disease with 6–7 million people infected worldwide,
and there is no effective treatment. Therefore, there is an urgent need to continue …

A good balance between hydrophilicity and lipophilicity is a prerequisite for all bioactive
compounds. If the hydrophilicity of a compound is low, its solubility in water will be meager …

Abstract Formation of Cu, Zn superoxide dismutase 1 (SOD1) protein inclusions within motor
neurons is one of the principal characteristics of SOD1-related amyotrophic lateral sclerosis …