Cilia mediate an astonishing diversity of processes. Recent advances provide unexpected
insights into the regulatory mechanisms of cilium formation, and reveal diverse regulatory …

Cilia and flagella are microtubule-based organelles whose assembly requires a motile
process, known as intraflagellar transport (IFT), to bring tubulin and other components to the …

BACKGROUND The precise movement of proteins and vesicles is an essential ability for all
eukaryotic cells. Nowhere is this more evident than during the remarkable transformation …

Primary cilia are immotile organelles known for their roles in development and cell signaling.
Defects in primary cilia result in a range of disorders named ciliopathies. Because this …

As motile organelles and sensors, cilia play pivotal roles in cell physiology, development
and organ homeostasis. Ciliary defects are associated with a class of cilia-related diseases …

Primary cilia play a key role in the ability of cells to respond to extracellular stimuli, such as
signaling molecules and environmental cues. These sensory organelles are crucial to the …

The unicellular green alga, Chlamydomonas reinhardti i, has played a central role in
discovering much of what is currently known about the composition, assembly, and function …

As cells grow, the size and number of their internal organelles increase in order to keep up
with increased metabolic requirements. Abnormal size of organelles is a hallmark of cancer …

The effects of cilium length on the dynamics of cilia motion were investigated by high-speed
video microscopy of uniciliated mutants of the swimming alga, Chlamydomonas reinhardtii …

Why some genes are more popular than others remains an open question, but one example
of this phenomenon involves the genes controlling planar cell polarity (PCP), the …