A biological classification of Huntington's disease: the Integrated Staging System
The current research paradigm for Huntington's disease is based on participants with overt
clinical phenotypes and does not address its pathophysiology nor the biomarker changes …
clinical phenotypes and does not address its pathophysiology nor the biomarker changes …
[HTML][HTML] The Wisconsin Registry for Alzheimer's Prevention: a review of findings and current directions
Abstract The Wisconsin Registry for Alzheimer's Prevention is a longitudinal observational
cohort study enriched with persons with a parental history (PH) of probable Alzheimer's …
cohort study enriched with persons with a parental history (PH) of probable Alzheimer's …
Recent advances in neuropsychological test interpretation for clinical practice
Much attention in the field of clinical neuropsychology has focused on adapting to the
modern healthcare environment by advancing telehealth and promoting technological …
modern healthcare environment by advancing telehealth and promoting technological …
Neuroimaging of tissue microstructure as a marker of neurodegeneration in the AT (N) framework: defining abnormal neurodegeneration and improving prediction of …
Background Alzheimer's disease involves accumulating amyloid (A) and tau (T) pathology,
and progressive neurodegeneration (N), leading to the development of the AD clinical …
and progressive neurodegeneration (N), leading to the development of the AD clinical …
Validity evidence for the research category,“cognitively unimpaired–declining,” as a risk marker for mild cognitive impairment and Alzheimer's disease
While clinically significant cognitive impairment is the key feature of the symptomatic stages
of the Alzheimer's disease (AD) continuum, subtle cognitive decline is now known to occur …
of the Alzheimer's disease (AD) continuum, subtle cognitive decline is now known to occur …
Using robust normative data to investigate the neuropsychology of cognitive aging
Objective The extent to which increasing age is associated with impairment in cognitive
function, termed cognitive aging, may have been overestimated in prior studies. The …
function, termed cognitive aging, may have been overestimated in prior studies. The …
Mayo Normative Studies: Amyloid and Neurodegeneration Negative Normative Data for the Auditory Verbal Learning Test and Sex-Specific Sensitivity to Mild …
NH Stricker, TJ Christianson… - Journal of …, 2024 - journals.sagepub.com
Background: Conventional normative samples include individuals with undetected
Alzheimer's disease neuropathology, lowering test sensitivity for cognitive impairment …
Alzheimer's disease neuropathology, lowering test sensitivity for cognitive impairment …
The complex burden of determining prevalence rates of mild cognitive impairment: a systematic review
Mild cognitive impairment (MCI) is a syndrome characterized by a decline in cognitive
performance greater than expected for an individual's age and education level, but that does …
performance greater than expected for an individual's age and education level, but that does …
Associations between performance on an abbreviated CogState battery, other measures of cognitive function, and biomarkers in people at risk for Alzheimer's disease
AM Racine, LR Clark, SE Berman… - Journal of …, 2016 - content.iospress.com
It is not known whether computerized cognitive assessments, like the CogState battery, are
sensitive to preclinical cognitive changes or pathology in people at risk for Alzheimer's …
sensitive to preclinical cognitive changes or pathology in people at risk for Alzheimer's …
Longitudinal plasma phosphorylated‐tau217 and other related biomarkers in a non‐demented Alzheimer's risk‐enhanced sample
INTRODUCTION Understanding longitudinal change in key plasma biomarkers will aid in
detecting presymptomatic Alzheimer's disease (AD). METHODS Serial plasma samples from …
detecting presymptomatic Alzheimer's disease (AD). METHODS Serial plasma samples from …