Long noncoding RNAs in cancer metastasis

SJ Liu, HX Dang, DA Lim, FY Feng… - Nature Reviews Cancer, 2021 - nature.com
Metastasis is a major contributor to cancer-associated deaths. It is characterized by a
multistep process that occurs through the acquisition of molecular and phenotypic changes …

The long and short non-coding RNAs modulating EZH2 signaling in cancer

S Mirzaei, MH Gholami, K Hushmandi… - Journal of Hematology & …, 2022 - Springer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …

Involvement of lncRNAs in cancer cells migration, invasion and metastasis: cytoskeleton and ECM crosstalk

M Ahmad, LB Weiswald, L Poulain, C Denoyelle… - Journal of Experimental …, 2023 - Springer
Cancer is the main cause of death worldwide and metastasis is a major cause of poor
prognosis and cancer-associated mortality. Metastatic conversion of cancer cells is a …

Noncoding RNA: RNA regulatory networks in cancer

JJ Chan, Y Tay - International journal of molecular sciences, 2018 - mdpi.com
Noncoding RNAs (ncRNAs) constitute the majority of the human transcribed genome. This
largest class of RNA transcripts plays diverse roles in a multitude of cellular processes, and …

Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: roles in cancer progression and therapeutic response

M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …

Interleukin-6 mediated inflammasome activation promotes oral squamous cell carcinoma progression via JAK2/STAT3/Sox4/NLRP3 signaling pathway

L **ao, X Li, P Cao, W Fei, H Zhou, N Tang… - Journal of Experimental & …, 2022 - Springer
Abstract Background Interleukin-6 (IL-6) has been reported to be critical in oral squamous
cell carcinoma (OSCC). However, the set of pathways that IL-6 might activate in OSCC are …

Extracellular vesicles from human embryonic stem cell-derived cardiovascular progenitor cells promote cardiac infarct healing through reducing cardiomyocyte death …

Q Wu, J Wang, WLW Tan, Y Jiang, S Wang, Q Li… - Cell Death & …, 2020 - nature.com
Human pluripotent stem cells (hPSCs)-derived cardiovascular progenitor cells (CVPCs) are
a promising source for myocardial repair, while the mechanisms remain largely unknown …

LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling

S Zhang, H Ma, D Zhang, S **e, W Wang, Q Li… - Cell death & …, 2018 - nature.com
Numerous findings have demonstrated that long noncoding RNA (lncRNA) dysregulation
plays a key role in many human neoplasms, including tongue squamous cell carcinoma …

Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

R Li, Y Wang, X Zhang, M Feng, J Ma, J Li, X Yang… - Molecular cancer, 2019 - Springer
Background Lysyl oxidase-like 4 (LOXL4) has been found to be dysregulated in several
human malignancies, including hepatocellular carcinoma (HCC). However, the role of …

Tumor metastasis: Mechanistic insights and therapeutic interventions

M Liu, J Yang, B Xu, X Zhang - MedComm, 2021 - Wiley Online Library
Cancer metastasis is responsible for the vast majority of cancer‐related deaths worldwide. In
contrast to numerous discoveries that reveal the detailed mechanisms leading to the …