Molecular mechanism of VEGF and its role in pathological angiogenesis

A Ahmad, MI Nawaz - Journal of cellular biochemistry, 2022 - Wiley Online Library
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …

[HTML][HTML] Glia–neuron interactions in the mammalian retina

E Vecino, FD Rodriguez, N Ruzafa, X Pereiro… - Progress in retinal and …, 2016 - Elsevier
The mammalian retina provides an excellent opportunity to study glia–neuron interactions
and the interactions of glia with blood vessels. Three main types of glial cells are found in …

[HTML][HTML] Diabetic retinopathy: an overview on mechanisms, pathophysiology and pharmacotherapy

P Ansari, N Tabasumma, NN Snigdha, NH Siam… - Diabetology, 2022 - mdpi.com
Diabetes mellitus is one of the most frequently occurring metabolic disorders (DMs),
impairing healthy life around the globe, with mild-to-severe secondary complications. DM is …

Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases

N Cuenca, L Fernández-Sánchez, L Campello… - Progress in retinal and …, 2014 - Elsevier
Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Human vitreous in proliferative diabetic retinopathy: characterization and translational implications

IM Nawaz, S Rezzola, A Cancarini, A Russo… - Progress in retinal and …, 2019 - Elsevier
Diabetic retinopathy (DR) is one of the leading causes of visual impairment in the working-
age population. DR is a progressive eye disease caused by long-term accumulation of …

Recent insights into the etiopathogenesis of diabetic retinopathy and its management

A Biswas, AD Choudhury, S Agrawal… - Journal of Ocular …, 2024 - liebertpub.com
Purpose: Diabetic retinopathy (DR) is a microvascular retinal disease associated with
chronic diabetes mellitus, characterized by the damage of blood vessels in the eye. It is …

Flavonoid naringenin attenuates oxidative stress, apoptosis and improves neurotrophic effects in the diabetic rat retina

DI Al-Dosari, MM Ahmed, SS Al-Rejaie, AS Alhomida… - Nutrients, 2017 - mdpi.com
Diabetic retinopathy (DR) is one of the leading causes of decreased vision and blindness
worldwide. Diabetes-induced oxidative stress is believed to be the key factor that initiates …

Circadian clock organization in the retina: From clock components to rod and cone pathways and visual function

JD Bhoi, M Goel, CP Ribelayga, SC Mangel - Progress in retinal and eye …, 2023 - Elsevier
Abstract Circadian (24-h) clocks are cell-autonomous biological oscillators that orchestrate
many aspects of our physiology on a daily basis. Numerous circadian rhythms in …

Relationships between neurodegeneration and vascular damage in diabetic retinopathy

MG Rossino, M Dal Monte, G Casini - Frontiers in neuroscience, 2019 - frontiersin.org
Diabetic retinopathy (DR) is a common complication of diabetes and constitutes a major
cause of vision impairment and blindness in the world. DR has long been described …

Diabetic retinopathy–biomolecules and multiple pathophysiology

H Ahsan - Diabetes & Metabolic Syndrome: Clinical Research & …, 2015 - Elsevier
One of the major complications in patients with diabetes is diabetic retinopathy (DR), a
leading cause of blindness worldwide. It causes visual impairment and finally blindness, a …