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Advancing Synthetic Hydrogels through Nature‐Inspired Materials Chemistry
Synthetic extracellular matrix (ECM) mimics that can recapitulate the complex biochemical
and mechanical nature of native tissues are needed for advanced models of development …
and mechanical nature of native tissues are needed for advanced models of development …
Engineered protein hydrogels as biomimetic cellular scaffolds
The biochemical and biophysical properties of the extracellular matrix (ECM) play a pivotal
role in regulating cellular behaviors such as proliferation, migration, and differentiation …
role in regulating cellular behaviors such as proliferation, migration, and differentiation …
Novel natural polymer‐based hydrogel patches with Janus asymmetric‐adhesion for emergency hemostasis and wound healing
L Sun, J Zhou, J Lai, X Zheng, H Wang… - Advanced Functional …, 2024 - Wiley Online Library
An asymmetrical wound dressing functions akin to human skin by serving as a protective
barrier between a wound and its immediate environment. However, significant challenges …
barrier between a wound and its immediate environment. However, significant challenges …
Harnessing mechanical stress with viscoelastic biomaterials for periodontal ligament regeneration
JJ Zhang, X Li, Y Tian, JK Zou, D Gan… - Advanced …, 2024 - Wiley Online Library
The viscoelasticity of mechanically sensitive tissues such as periodontal ligaments (PDLs) is
key in maintaining mechanical homeostasis. Unfortunately, PDLs easily lose viscoelasticity …
key in maintaining mechanical homeostasis. Unfortunately, PDLs easily lose viscoelasticity …
[HTML][HTML] Schiff base crosslinked hyaluronic acid hydrogels with tunable and cell instructive time-dependent mechanical properties
TB Kohlan, Y Wen, C Mini, A Finne-Wistrand - Carbohydrate Polymers, 2024 - Elsevier
The dynamic interplay between cells and their native extracellular matrix (ECM) influences
cellular behavior, imposing a challenge in biomaterial design. Dynamic covalent hydrogels …
cellular behavior, imposing a challenge in biomaterial design. Dynamic covalent hydrogels …
Substrate stress relaxation regulates neural stem cell fate commitment
Adult neural stem cells (NSCs) reside in the dentate gyrus of the hippocampus, and their
capacity to generate neurons and glia plays a role in learning and memory. In addition …
capacity to generate neurons and glia plays a role in learning and memory. In addition …
Viscoelastic cues to induce stem cell migration and neuronal differentiation in cell-free hydrogel-assisted TBI recovery
X Liu, C Wu, Y Zhang, G Li, S Chen, Z Chen… - Chemical Engineering …, 2024 - Elsevier
The concept of tissue-inducing biomaterials, such as osteoinductive biomaterials, has
inspired the design of regenerative material with biomimetic cues to manipulate cell/tissue …
inspired the design of regenerative material with biomimetic cues to manipulate cell/tissue …
Multi‐Functional Gelatin‐Dithiolane Hydrogels for Tissue Engineering
Biomaterials that integrate multiple functionalities, mimic the extracellular matrix (ECM)
microenvironment to support cellular growth, and adhere robustly to damaged tissues are …
microenvironment to support cellular growth, and adhere robustly to damaged tissues are …
Complex in vitro models positioned for impact to drug testing in pharma: a review
S Kang, EC Chen, H Cifuentes, G Cole, J Graham… - …, 2024 - iopscience.iop.org
Recent years have seen the creation and popularization of various complex in vitro models
(CIVMs), such as organoids and organs-on-chip, as a technology with the potential to …
(CIVMs), such as organoids and organs-on-chip, as a technology with the potential to …
[HTML][HTML] Emerging hydrogel therapies for translating brain disease: Materials, mechanisms, and recent research
X Lu, Y Luo, X Hu, J Chu, S Li, M Hao, J Zhuang… - Materials Today …, 2024 - Elsevier
Brain diseases, encompassing neurodegenerative disorders, strokes, and brain tumors,
represent significant medical conditions with profound implications for human health. The …
represent significant medical conditions with profound implications for human health. The …