Macroautophagy/autophagy is an evolutionarily conserved pathway responsible for clearing
cytosolic aggregated proteins, damaged organelles or invading microorganisms …

Reactive oxygen species (ROS) initially considered as only damaging agents in living
organisms further were found to play positive roles also. This paper describes ROS …

The endoplasmic reticulum (ER) is not only responsible for protein synthesis and folding but
also plays a critical role in sensing cellular stress and maintaining cellular homeostasis …

Atherogenesis, the formation of atherosclerotic plaques, is a complex process that involves
several mechanisms, including endothelial dysfunction, neovascularization, vascular …

Reactive oxygen species (ROS) are pervasive signaling molecules in biological systems. In
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …

Rationale: The rennin-angiotensin-aldosterone system (RAAS) plays a critical role in the
pathogenesis of diabetic cardiomyopathy, but the role of a member of RAAS, angiotensin IV …

Cancer cells are characterized by altered glucose metabolism known as the Warburg effect
in which aerobic glycolysis is increased. Glucose is converted to lactate even under …

Macroautophagy/autophagy is a degradative process essential for various cellular
processes. We previously demonstrated that autophagy-deficiency causes myoblast …

Pyrazolone is a well-known influential synthon for the synthesis of many molecules which
hold remarkable potential in the advancement of functional materials, coordination …

Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …