We review the behavior of theoretical models of excitable systems driven by Gaussian white
noise. We focus mainly on those general properties of such systems that are due to noise …

Kléber, André G., and Yoram Rudy. Basic Mechanisms of Cardiac Impulse Propagation and
Associated Arrhythmias. Physiol Rev 84: 431–488, 2004; 10.1152/physrev. 00025.2003 …

Wave propagation in ventricular muscle is rendered highly anisotropic by the intramural
rotation of the fiber. This rotational anisotropy is especially important because it can produce …

Many mechanisms have been proposed to explain ventricular fibrillation, which is the
precursor to sudden cardiac death, the leading cause ofdeath in the industrialized world (1) …

This paper reports the results of a theoretical investigation of spiral wave breakup in model
equations of action potential propagation in cardiac tissue. A general formulation of these …

Rotors or vortex action potentials with a diameter of about 1 centimeter and a rotation period
of about 0.1 second occur in normal myocardium just before transition to fibrillation, a …

In a normal human life span, the heart beats about 2–3 billion times. Under diseased
conditions, a heart may lose its normal rhythm and degenerate suddenly into much faster …

Multiple electrode map** of the ventricles during complex tachyarrhythmias has revealed
focal subendocardial activation whose mechanism remains unexplained. We hypothesized …

Background Ventricular tachycardia may result from vortexlike reentrant excitation of the
myocardium. Our general hypothesis is that in the structurally normal heart, these …

A" brain defibrillator" may be closer than we think. An epileptic seizure involves a
paroxysmal change in the activity of millions of neurons. Feedback control of seizures would …