Mannheimia haemolytica serotype S1 is considered the predominant cause of bovine
pneumonic pasteurellosis, or ship** fever. Various virulence factors allow M haemolytica …

Exotoxins play a central role in the pathologies caused by most major bacterial animal
pathogens. The large variety of vertebrate and invertebrate hosts in the animal kingdom is …

Mannheimia haemolytica is an important member of the bovine respiratory disease complex,
which is characterized by abundant neutrophil infiltration into the alveoli and fibrin …

RTX toxins are bacterial pore-forming toxins that are particularly abundant among
pathogenic species of Pasteurellaceae, in which they play a major role in virulence. RTX …

Signal peptides of membrane proteins are cleaved by endoplasmic reticulum-resident signal
peptidase, and thus, are not present on mature membrane proteins. Here, we report that …

Mannheimia haemolytica leukotoxin (LKT) is a known cause of bovine respiratory disease
(BRD) which results in severe economic losses in the cattle industry (up to USD 1 billion per …

The ruminant-specific leukotoxin (Lkt) of Mannheimia haemolytica is the key virulence factor
contributing to the pathogenesis of lung injury in bovine pneumonic pasteurellosis. Previous …

This study investigated via polymerase chain reaction (PCR) three main serotypes (A1, A2,
and A6) and nine virulence-associated genes in 71 ovine and caprine Mannheimia …

Mannheimia haemolytica consistently causes fatal bronchopneumonia in bighorn sheep
(BHS; Ovis canadensis) under natural and experimental conditions. Leukotoxin is the …

Background Mannheimia haemolytica is one of the main agents of domestic pneumonic
mannheimiosis, but a proper vaccine has not been explored in IRAN. Methods and Results …