Selective carbon–carbon bond cleavage of cyclopropanols

TR McDonald, LR Mills, MS West… - Chemical …, 2020 - ACS Publications
The carbon–carbon (C–C) bond cleavage of cyclopropanols is a wide area of research with
much current activity. This review highlights new developments in this area over the past two …

Creating stereocenters within acyclic systems by C–C bond cleavage of cyclopropanes

Y Cohen, A Cohen, I Marek - Chemical Reviews, 2020 - ACS Publications
Recent developments in the stereoselective synthesis of polysubstituted cyclopropanes
nowadays allow chemists to easily access these strained rings with high diastereo-and …

Cobalt-catalyzed diastereo-and enantioselective carbon–carbon bond forming reactions of cyclobutenes

Z Liang, L Wang, Y Wang, L Wang… - Journal of the …, 2023 - ACS Publications
Catalytic enantioselective functionalization of cyclobutenes constitutes a general and
modular strategy for construction of enantioenriched complex cyclobutanes bearing multiple …

Intramolecular photochemical [2+ 1]-cycloadditions of nucleophilic siloxy carbenes

A Bunyamin, C Hua, A Polyzos, DL Priebbenow - Chemical Science, 2022 - pubs.rsc.org
Visible light induced singlet nucleophilic carbenes undergo rapid [2+ 1]-cycloaddition with
tethered olefins to afford unique bicyclo [3.1. 0] hexane and bicyclo [4.1. 0] heptane …

Development and applications of water-compatible reactions: a journey to be continued

MZ Lu, TP Loh - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus The pursuit of novel and eco-friendly methods in organic synthesis is gaining
prominence, with a strong emphasis on green transformations using renewable and …

On the Origin of Rh-Catalyzed Selective Ring-Opening Amidation of Substituted Cyclopropanols to Access β2-Amino Ketones

M Lee, J Heo, D Kim, S Chang - Journal of the American Chemical …, 2022 - ACS Publications
β2-Amino carbonyls, an α-substituted β-amino scaffold, hold a prominent place in the
development of new pharmaceuticals and peptidomimetics. Herein, we report a highly …

Organophotocatalytic carbo-heterofunctionalization of unactivated olefins with pendant nucleophiles

DM Fischer, M Freis, WM Amberg, H Lindner… - Chemical …, 2023 - pubs.rsc.org
We report the difunctionalization of unactivated, terminal olefins through intermolecular
addition of α-bromoketones,-esters, and-nitriles followed by formation of 4-to 6-membered …

A Homo‐Mannich Reaction Strategy Enables Collective Access to Ibophyllidine, Aspidosperma, Kopsia, and Melodinus Alkaloids

D Jiang, P Tang, H **ong, S Lei… - Angewandte Chemie …, 2023 - Wiley Online Library
We report here a homo‐Mannich reaction of cyclopropanol with an iminium ion, generated
by an asymmetric allylic dearomatization of indole, to construct a tricyclic hydrocarbazole …

Iron-catalyzed ring-opening reactions of cyclopropanols with alkenes and TBHP: synthesis of 5-oxo peroxides

C Lou, X Wang, L Lv, Z Li - Organic Letters, 2021 - ACS Publications
The ring opening of cyclopropanols is rarely used in multicomponent reactions. Herein we
report the three-component reaction of cyclopropanols with alkenes and tert-butyl …

Enantioselective conjugate addition of catalytically generated zinc homoenolate

Y Sekiguchi, N Yoshikai - Journal of the American Chemical …, 2021 - ACS Publications
We report herein an enantioselective conjugate addition reaction of a zinc homoenolate,
catalytically generated via ring opening of a cyclopropanol, to an α, β-unsaturated ketone …