Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
Electrical stimulation affects neural stem cell fate and function in vitro
Electrical stimulation (ES) has been applied in cell culture system to enhance neural stem
cell (NSC) proliferation, neuronal differentiation, migration, and integration. According to the …
cell (NSC) proliferation, neuronal differentiation, migration, and integration. According to the …
Grooved fibers: Preparation principles through electrospinning and potential applications
L Zhan, J Deng, Q Ke, X Li, Y Ouyang, C Huang… - Advanced Fiber …, 2022 - Springer
The surface morphology of micro-and nano-scale fiber determines its application to a great
extent. At present, a variety of secondary morphology of microfibers and nanofibers, such as …
extent. At present, a variety of secondary morphology of microfibers and nanofibers, such as …
[HTML][HTML] Engineered M13 phage as a novel therapeutic bionanomaterial for clinical applications: From tissue regeneration to cancer therapy
C Chang, W Guo, X Yu, C Guo, N Zhou, X Guo… - Materials Today Bio, 2023 - Elsevier
Bacteriophages (phages) are nanostructured viruses with highly selective antibacterial
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …
Electrical stimulation promotes stem cell neural differentiation in tissue engineering
H Cheng, Y Huang, H Yue, Y Fan - Stem cells international, 2021 - Wiley Online Library
Nerve injuries and neurodegenerative disorders remain serious challenges, owing to the
poor treatment outcomes of in situ neural stem cell regeneration. The most promising …
poor treatment outcomes of in situ neural stem cell regeneration. The most promising …
Antioxidative and conductive nanoparticles-embedded cell niche for neural differentiation and spinal cord injury repair
C Wu, S Chen, T Zhou, K Wu, Z Qiao… - … applied materials & …, 2021 - ACS Publications
Following spinal cord injury (SCI), the transmission of electrical signals is interrupted, and an
oxidative microenvironment is generated, hindering nerve regeneration and functional …
oxidative microenvironment is generated, hindering nerve regeneration and functional …
A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion
Islet transplantation for type 1 diabetes treatment has been limited by the need for lifelong
immunosuppression regimens. This challenge has prompted the development of …
immunosuppression regimens. This challenge has prompted the development of …
Delivering mechanical stimulation to cells: state of the art in materials and devices design
Y Zhang, P Habibovic - Advanced Materials, 2022 - Wiley Online Library
Biochemical signals, such as growth factors, cytokines, and transcription factors are known
to play a crucial role in regulating a variety of cellular activities as well as maintaining the …
to play a crucial role in regulating a variety of cellular activities as well as maintaining the …
Piezoelectric nanotopography induced neuron‐like differentiation of stem cells
The biophysical characteristics of the extracellular matrix, such as nanotopography and
bioelectricity, have a profound influence on cell proliferation, adhesion, differentiation, etc …
bioelectricity, have a profound influence on cell proliferation, adhesion, differentiation, etc …
Coordinated Biophysical Stimulation of MSCs via Electromagnetized Au‐Nanofiber Matrix Regulates Cytoskeletal‐to‐Nuclear Mechanoresponses and Lineage …
Biophysical stimulation regulates stem cell functions, including proliferation and
differentiation. Matrix nanotopography and external forces, such as electromagnetic fields …
differentiation. Matrix nanotopography and external forces, such as electromagnetic fields …