NLR receptors in plant immunity: making sense of the alphabet soup
Plants coordinately use cell‐surface and intracellular immune receptors to perceive
pathogens and mount an immune response. Intracellular events of pathogen recognition are …
pathogens and mount an immune response. Intracellular events of pathogen recognition are …
[HTML][HTML] Tactics of host manipulation by intracellular effectors from plant pathogenic fungi
Fungal pathogens can secrete hundreds of effectors, some of which are known to promote
host susceptibility. This biological complexity, together with the lack of genetic tools in some …
host susceptibility. This biological complexity, together with the lack of genetic tools in some …
New recognition specificity in a plant immune receptor by molecular engineering of its integrated domain
S Cesari, Y **, N Declerck, V Chalvon… - Nature …, 2022 - nature.com
Plant nucleotide-binding and leucine-rich repeat domain proteins (NLRs) are immune
sensors that recognize pathogen effectors. Here, we show that molecular engineering of the …
sensors that recognize pathogen effectors. Here, we show that molecular engineering of the …
Effector target-guided engineering of an integrated domain expands the disease resistance profile of a rice NLR immune receptor
A subset of plant intracellular NLR immune receptors detect effector proteins, secreted by
phytopathogens to promote infection, through unconventional integrated domains which …
phytopathogens to promote infection, through unconventional integrated domains which …
Surface frustration re-patterning underlies the structural landscape and evolvability of fungal orphan candidate effectors
Pathogens secrete effector proteins to subvert host physiology and cause disease. Effectors
are engaged in a molecular arms race with the host resulting in conflicting evolutionary …
are engaged in a molecular arms race with the host resulting in conflicting evolutionary …
Bioengineering a plant NLR immune receptor with a robust binding interface toward a conserved fungal pathogen effector
Bioengineering of plant immune receptors has emerged as a key strategy for generating
novel disease resistance traits to counteract the expanding threat of plant pathogens to …
novel disease resistance traits to counteract the expanding threat of plant pathogens to …
A blast fungus zinc-finger fold effector binds to a hydrophobic pocket in host Exo70 proteins to modulate immune recognition in rice
JC De la Concepcion, K Fujisaki… - Proceedings of the …, 2022 - National Acad Sciences
Exocytosis plays an important role in plant–microbe interactions, in both pathogenesis and
symbiosis. Exo70 proteins are integral components of the exocyst, an octameric complex …
symbiosis. Exo70 proteins are integral components of the exocyst, an octameric complex …
Multiple variants of the fungal effector AVR-Pik bind the HMA domain of the rice protein OsHIPP19, providing a foundation to engineer plant defense
Microbial plant pathogens secrete effector proteins, which manipulate the host to promote
infection. Effectors can be recognized by plant intracellular nucleotide-binding leucine-rich …
infection. Effectors can be recognized by plant intracellular nucleotide-binding leucine-rich …
Molecular engineering of plant immune receptors for tailored crop disease resistance
L Cadiou, F Brunisholz, S Cesari, T Kroj - Current Opinion in Plant Biology, 2023 - Elsevier
The specific recognition of pathogen effectors by intracellular nucleotide-binding and
leucine-rich repeat domain receptors (NLRs) is an important component of plant immunity …
leucine-rich repeat domain receptors (NLRs) is an important component of plant immunity …
Show me your ID: NLR immune receptors with integrated domains in plants
Nucleotide-binding and leucine-rich repeat receptors (NLRs) are intracellular plant immune
receptors that recognize pathogen effectors secreted into the plant cell. Canonical NLRs …
receptors that recognize pathogen effectors secreted into the plant cell. Canonical NLRs …