Meniscal repair

C Stärke, S Kopf, W Petersen, R Becker - Arthroscopy: the journal of …, 2009 - Elsevier
The meniscus plays an important role in preventing osteoarthritis of the knee. Repair of a
meniscal lesion should be strongly considered if the tear is peripheral and longitudinal, with …

Mimicking growth factors: role of small molecule scaffold additives in promoting tissue regeneration and repair

N Goonoo, A Bhaw-Luximon - RSC advances, 2019 - pubs.rsc.org
The primary aim of tissue engineering scaffolds is to mimic the in vivo environment and
promote tissue growth. In this quest, a number of strategies have been developed such as …

Meniscus structure in human, sheep, and rabbit for animal models of meniscus repair

A Chevrier, M Nelea, MB Hurtig… - Journal of …, 2009 - Wiley Online Library
Meniscus injury is a frequently encountered clinical orthopedic issue and is
epidemiologically correlated to osteoarthritis. The development of new treatments for …

Programmed biomolecule delivery to enable and direct cell migration for connective tissue repair

F Qu, JL Holloway, JL Esterhai, JA Burdick… - Nature …, 2017 - nature.com
Dense connective tissue injuries have limited repair, due to the paucity of cells at the wound
site. We hypothesize that decreasing the density of the local extracellular matrix (ECM) in …

Role of mesenchymal stem cells in tissue engineering of meniscus

J Zellner, M Mueller, A Berner… - … Research Part A, 2010 - Wiley Online Library
Tissue engineering is a promising approach for the treatment of tissue defects.
Mesenchymal stem cells are of potential use as a source of repair cells or of important …

Meniscus repair and regeneration: a systematic review from a basic and translational science perspective

J Twomey-Kozak, C Jayasuriya - Clinics in sports medicine, 2020 - pmc.ncbi.nlm.nih.gov
Meniscus injuries are among the most common athletic injuries and result in functional
impairment in the knee. Repair is crucial for pain relief and prevention of degenerative joint …

Tissue engineering and regenerative medicine strategies in meniscus lesions

H Pereira, AM Frias, JM Oliveira… - Arthroscopy: The journal …, 2011 - Elsevier
PURPOSE: The aim of this systematic review was to address tissue engineering and
regenerative medicine (TERM) strategies applied to the meniscus, specifically (1) clinical …

Stem cell‐based tissue‐engineering for treatment of meniscal tears in the avascular zone

J Zellner, K Hierl, M Mueller, C Pfeifer… - … Research Part B …, 2013 - Wiley Online Library
Meniscal tears in the avascular zone have a poor self‐healing potential, however partial
meniscectomy predisposes the knee for early osteoarthritis. Tissue engineering with …

Hyaluronic acid promotes proliferation and migration of human meniscus cells via a CD44-dependent mechanism

T Murakami, S Otsuki, Y Okamoto… - Connective tissue …, 2019 - Taylor & Francis
Purpose: Treatment of meniscal injury is important for osteoarthritis (OA) prevention.
Meniscus cells are divided between inner and outer cells, which have different …

In vitro repair of meniscal radial tear with hydrogels seeded with adipose stem cells and TGF-β3

H Sasaki, BB Rothrauff, PG Alexander… - … American journal of …, 2018 - journals.sagepub.com
Background: Radial tears of the meniscus are a common knee injury, frequently resulting in
osteoarthritis. To date, there are no established, effective treatments for radial tears. Adipose …