Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease
S Urban, C Neumann-Haefelin, P Lampertico - Gut, 2021 - gut.bmj.com
Approximately 5% of individuals infected with hepatitis B virus (HBV) are coinfected with
hepatitis D virus (HDV). Chronic HBV/HDV coinfection is associated with an unfavourable …
hepatitis D virus (HDV). Chronic HBV/HDV coinfection is associated with an unfavourable …
Therapeutic strategies for hepatitis B virus infection: towards a cure
GC Fanning, F Zoulim, J Hou, A Bertoletti - Nature reviews Drug …, 2019 - nature.com
Chronic hepatitis B virus (HBV) infection is a common cause of liver disease globally, with a
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …
Hepatitis virus and hepatocellular carcinoma: recent advances
C Shen, X Jiang, M Li, Y Luo - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a global health challenge. Hepatitis
virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …
virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …
Hepatitis B virus persistence and reactivation
Y Shi, M Zheng - bmj, 2020 - bmj.com
Hepatitis B virus (HBV) infection causes chronic hepatitis and has long term complications.
Individuals ever infected with HBV are at risk of viral reactivation under certain …
Individuals ever infected with HBV are at risk of viral reactivation under certain …
Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition
Glucose metabolism and innate immunity evolved side-by-side. It is unclear if and how the
two systems interact with each other during hepatitis B virus (HBV) infections and, if so …
two systems interact with each other during hepatitis B virus (HBV) infections and, if so …
[HTML][HTML] A review on hepatitis D: From virology to new therapies
N Mentha, S Clément, F Negro, D Alfaiate - Journal of advanced research, 2019 - Elsevier
Hepatitis delta virus (HDV) is a defective virus that requires the hepatitis B virus (HBV) to
complete its life cycle in human hepatocytes. HDV virions contain an envelope incorporating …
complete its life cycle in human hepatocytes. HDV virions contain an envelope incorporating …
[HTML][HTML] Hepatitis B virus does not interfere with innate immune responses in the human liver
A Suslov, T Boldanova, X Wang, S Wieland, MH Heim - Gastroenterology, 2018 - Elsevier
Background & Aims Most viruses are detected at early stages of cell infection and induce an
innate immune response mediated by production of interferons (IFNs). IFNs induce …
innate immune response mediated by production of interferons (IFNs). IFNs induce …
Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes
Z Zhang, C Filzmayer, Y Ni, H Sültmann, P Mutz… - Journal of …, 2018 - Elsevier
Background & Aims Hepatitis B virus (HBV) and D virus (HDV) co-infections cause the most
severe form of viral hepatitis. HDV induces an innate immune response, but it is unknown …
severe form of viral hepatitis. HDV induces an innate immune response, but it is unknown …
Interferon and hepatitis B: current and future perspectives
J Ye, J Chen - Frontiers in Immunology, 2021 - frontiersin.org
Chronic hepatitis B virus (HBV) infection remains a major health burden worldwide for which
there is still no effective curative treatment. Interferon (IFN) consists of a group of cytokines …
there is still no effective curative treatment. Interferon (IFN) consists of a group of cytokines …
Enveloped viruses distinct from HBV induce dissemination of hepatitis D virus in vivo
J Perez-Vargas, F Amirache, B Boson, C Mialon… - Nature …, 2019 - nature.com
Hepatitis D virus (HDV) doesn't encode envelope proteins for packaging of its
ribonucleoprotein (RNP) and typically relies on the surface glycoproteins (GPs) from …
ribonucleoprotein (RNP) and typically relies on the surface glycoproteins (GPs) from …