We discuss the emerging new opportunity for building feedback‐rich computational models
of social systems using generative artificial intelligence. Referred to as generative agent …

Opioid overdose deaths remain a major public health crisis. We used a system dynamics
simulation model of the US opioid-using population age 12 and older to explore the impacts …

Alzheimer's disease (AD) is a complex neurological disorder characterized by accumulation
of amyloid plaques and neurofibrillary tangles. Long term investigation of AD pathogenesis …

Opioid misuse continues to cause significant harm. To investigate current research, we
conducted a sco** literature review of disease spread models of opioid misuse from …

An open‐label, randomized, crossover study in healthy volunteers compared the reversal of
remifentanil‐induced respiratory depression by intranasal (IN) naloxone hydrochloride (4 …

Nalmefene is a high‐affinity, long‐duration opioid antagonist that was approved in 1995 as
an injection for the treatment of opiate overdose, but subsequently withdrawn (2008) for …

Background Community pharmacies are well-positioned to improve the health of people
with opioid use disorder and who use drugs by providing naloxone and other essential …

Introduction Using a validated translational model that quantitatively predicts opioid-induced
respiratory depression and cardiac arrest, we compared cardiac arrest events caused by …