Cardiovascular diseases (CVDs), such as ischaemic heart disease, cardiomyopathy,
atherosclerosis, hypertension, stroke and heart failure, are among the leading causes of …

ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …

In cartilage, chondrocytes are responsible for the biogenesis and maintenance of the
extracellular matrix (ECM) composed of proteins, glycoproteins and proteoglycans. Various …

ER-phagy, literally endoplasmic reticulum (ER)-eating, defines the constitutive or regulated
clearance of ER portions within metazoan endolysosomes or yeast and plant vacuoles. The …

The endoplasmic reticulum (ER) is an organelle of nucleated cells that produces proteins,
lipids and oligosaccharides. ER volume and activity are increased upon induction of …

The endoplasmic reticulum (ER) is one of the most important cellular organelles and is
essential for cell homeostasis. Upon external stimulation, ER stress induces the unfolded …

The endoplasmic reticulum (ER) hosts linear polypeptides and fosters natural folding of
proteins through ER-residing chaperones and enzymes. Failure of the ER to align and …

Infection by many (+) RNA viruses is accompanied by ER-expansion and membrane
remodelling to form viral replication organelles, followed by assembly and secretion of viral …

The endoplasmic reticulum (ER) is a cellular organelle that is physiologically responsible for
protein folding, calcium homeostasis, and lipid biosynthesis. Pathological stimuli such as …

Efficient degradation of by‐products of protein biogenesis maintains cellular fitness.
Strikingly, the major biosynthetic compartment in eukaryotic cells, the endoplasmic reticulum …