Pyroptosis is closely associated with tumors and inflammatory diseases. By enhancing
pyroptosis, direct and immune-response-triggered deaths of tumor cells are increased …

Diabetic wound is one of the complications of diabetes and is not easy to heal. It often
evolves into chronic ulcers, and severe patients will face amputation. Compared with normal …

As a major late complication of diabetes, diabetic peripheral neuropathy (DPN) is the
primary reason for amputation. Nevertheless, there are no wonder drugs available …

Some chemotherapeutic agents, such as anthracyclines and oxaliplatin, can induce
immunogenic cell death (ICD) with additional immune responses against cancer. However …

There has been considerable interest in gene vectors and their role in regulating cellular
activities and treating diseases since the advent of nucleic acid drugs. MicroRNA (miR) …

Pyroptosis, a lytic form of cell death mediated by the gasdermin family, is characterized by
cell swelling and membrane rupture. Inducing pyroptosis in cancer cells can enhance …

Renal fibrosis is a common pathway toward chronic kidney disease (CKD) and is the main
pathological predecessor for end-stage renal disease; thus, preventing progressive CKD …

Liver fibrosis, an early stage of cirrhosis, with large number of patients and seriously
endangering health, has no viable treatment available currently. In this study, we choose …

Bone loss is prevalent in clinical pathological phenomena such as osteoporosis, which is
characterized by decreased osteoblast function and number, increased osteoclast activity …

Pulmonary fibrosis that occurs following lung injury is a progressive and fatal disease since
continual damage to lung tissue triggers the dysregulated inflammation response and …