The Circadian Syndrome: is the Metabolic Syndrome and much more!
Abstract The Metabolic Syndrome is a cluster of cardio‐metabolic risk factors and
comorbidities conveying high risk of both cardiovascular disease and type 2 diabetes. It is …
comorbidities conveying high risk of both cardiovascular disease and type 2 diabetes. It is …
[HTML][HTML] Molecular genetics of human obesity: A comprehensive review
Obesity and its related health complications is a major problem worldwide. Hypothalamus
and their signalling molecules play a critical role in the intervening and coordination with …
and their signalling molecules play a critical role in the intervening and coordination with …
[HTML][HTML] Genome-wide methylation profiles reveal quantitative views of human aging rates
The ability to measure human aging from molecular profiles has practical implications in
many fields, including disease prevention and treatment, forensics, and extension of life …
many fields, including disease prevention and treatment, forensics, and extension of life …
The osteological paradox 20 years later: past perspectives, future directions
More than 20 years ago, Wood et al.(Curr Anthropol 33: 343–370, 1992) published “The
Osteological Paradox: Problems of Inferring Prehistoric Health from Skeletal Samples,” in …
Osteological Paradox: Problems of Inferring Prehistoric Health from Skeletal Samples,” in …
Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species
Methylation of cytosines is a prototypic epigenetic modification of the DNA. It has been
implicated in various regulatory mechanisms across the animal kingdom and particularly in …
implicated in various regulatory mechanisms across the animal kingdom and particularly in …
Dietary and gut microbiota polyamines in obesity-and age-related diseases
The polyamines putrescine, spermidine, and spermine are widely distributed polycationic
compounds essential for cellular functions. Intracellular polyamine pools are tightly …
compounds essential for cellular functions. Intracellular polyamine pools are tightly …
Impact of obesity on male fertility, sperm function and molecular composition
Male obesity in reproductive-age men has nearly tripled in the past 30 y and coincides with
an increase in male infertility worldwide. There is now emerging evidence that male obesity …
an increase in male infertility worldwide. There is now emerging evidence that male obesity …
Physical activity in the prevention of human diseases: role of epigenetic modifications
Epigenetic modification refers to heritable changes in gene function that cannot be
explained by alterations in the DNA sequence. The current literature clearly demonstrates …
explained by alterations in the DNA sequence. The current literature clearly demonstrates …
Paternal obesity is associated with IGF2hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort
Background Data from epidemiological and animal model studies suggest that nutrition
during pregnancy may affect the health status of subsequent generations. These …
during pregnancy may affect the health status of subsequent generations. These …
Epigenomics, gestational programming and risk of metabolic syndrome
Epigenetic mechanisms are emerging as mediators linking early environmental exposures
during pregnancy with programmed changes in gene expression that alter offspring growth …
during pregnancy with programmed changes in gene expression that alter offspring growth …