Over the past 20 years, and particularly in the last decade, significant developmental
milestones have driven basic, translational, and clinical advances in the field of stem cell …

Quantum Fisher information matrix (QFIM) is a core concept in theoretical quantum
metrology due to the significant importance of quantum Cramér–Rao bound in quantum …

Understanding lineage specification during human pre-implantation development is a
gateway to improving assisted reproductive technologies and stem cell research. Here we …

Current understandings of cell specification in early mammalian pre-implantation
development are based mainly on mouse studies. The first lineage differentiation event …

Naïve human pluripotent stem cells (hPSCs) provide a unique experimental platform of cell
fate decisions during pre-implantation development, but their lineage potential remains …

Pluripotent stem cells (PSCs) isolated in vitro from embryonic stem cells (ESCs), induced
PSC (iPSC) and also post-implantation epiblast-derived stem cells (EpiSCs) are known for …

The reprogramming of human somatic cells to primed or naive induced pluripotent stem
cells recapitulates the stages of early embryonic development,,,,–. The molecular …

Pluripotent stem cells (PSCs) are characterized by their unique capacity for both unlimited
self-renewal and their potential to differentiate to all cell lineages contained within the three …

Human trophoblast stem cells (hTSCs) derived from blastocysts and first-trimester
cytotrophoblasts offer an unprecedented opportunity to study the placenta. However, access …

Our understanding of pluripotency remains limited: iPSC generation has only been
established for a few model species, pluripotent stem cell lines exhibit inconsistent …