Mitochondrial machineries for protein import and assembly
Mitochondria are essential organelles with numerous functions in cellular metabolism and
homeostasis. Most of the> 1,000 different mitochondrial proteins are synthesized as …
homeostasis. Most of the> 1,000 different mitochondrial proteins are synthesized as …
Importing mitochondrial proteins: machineries and mechanisms
Most mitochondrial proteins are synthesized on cytosolic ribosomes and must be imported
across one or both mitochondrial membranes. There is an amazingly versatile set of …
across one or both mitochondrial membranes. There is an amazingly versatile set of …
Mitochondrial protein import: from proteomics to functional mechanisms
Mitochondria contain∼ 1,000 different proteins, most of which are imported from the cytosol.
Two import pathways that direct proteins into the mitochondrial inner membrane and matrix …
Two import pathways that direct proteins into the mitochondrial inner membrane and matrix …
Role of platelet mitochondria: life in a nucleus-free zone
Platelets are abundant, small, anucleate circulating cells, serving many emerging
pathophysiological roles beyond hemostasis; including active critical roles in thrombosis …
pathophysiological roles beyond hemostasis; including active critical roles in thrombosis …
[HTML][HTML] The protein import machinery of mitochondria—a regulatory hub in metabolism, stress, and disease
Mitochondria fulfill central functions in bioenergetics, metabolism, and apoptosis. They
import more than 1,000 different proteins from the cytosol. It had been assumed that the …
import more than 1,000 different proteins from the cytosol. It had been assumed that the …
[BOOK][B] The structure of biological membranes
PL Yeagle - 2004 - taylorfrancis.com
Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …
biochemistry. Now more than ever, it is essential to update our current understanding of …
Multistep protein unfolding during nanopore translocation
Cells are divided into compartments and separated from the environment by lipid bilayer
membranes. Essential molecules are transported back and forth across the membranes. We …
membranes. Essential molecules are transported back and forth across the membranes. We …
[HTML][HTML] Mitochondrial protein import: common principles and physiological networks
Most mitochondrial proteins are encoded in the nucleus. They are synthesized as precursor
forms in the cytosol and must be imported into mitochondria with the help of different protein …
forms in the cytosol and must be imported into mitochondria with the help of different protein …
The peroxisomal importomer constitutes a large and highly dynamic pore
M Meinecke, C Cizmowski, W Schliebs, V Krüger… - Nature cell …, 2010 - nature.com
The peroxisomal protein import machinery differs fundamentally from known translocons
(endoplasmic reticulum, mitochondria, chloroplasts, bacteria) as it allows membrane …
(endoplasmic reticulum, mitochondria, chloroplasts, bacteria) as it allows membrane …
[HTML][HTML] Phosphatidylethanolamine and cardiolipin differentially affect the stability of mitochondrial respiratory chain supercomplexes
L Böttinger, SE Horvath, T Kleinschroth, C Hunte… - Journal of molecular …, 2012 - Elsevier
The mitochondrial inner membrane contains two non-bilayer‐forming phospholipids,
phosphatidylethanolamine (PE) and cardiolipin (CL). Lack of CL leads to destabilization of …
phosphatidylethanolamine (PE) and cardiolipin (CL). Lack of CL leads to destabilization of …