Unravelling the enigma of siRNA and aptamer mediated therapies against pancreatic cancer
Pancreatic cancer (PC) is a fatal disease that has a poor 5-year survival rate. The poor
prognosis can be attributed to both troublesome detections at the initial stage, which makes …
prognosis can be attributed to both troublesome detections at the initial stage, which makes …
[HTML][HTML] Liposome-based diagnostic and therapeutic applications for pancreatic cancer
Pancreatic cancer is one of the harshest and most challenging cancers to treat, often labeled
as incurable. Chemotherapy continues to be the most popular treatment yet yields a very …
as incurable. Chemotherapy continues to be the most popular treatment yet yields a very …
Polymeric micelles assisted combinatorial therapy: Is it new hope for pancreatic cancer?
Pancreatic cancer (PC) is a fatal disease that has a 5-year survival rate of less than 9%. It is
expected to rank second in cancer-related deaths across the United States by 2030. Out of …
expected to rank second in cancer-related deaths across the United States by 2030. Out of …
Targeted therapies for pancreatic cancer and hurdles ahead
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal cancers
with a median survival of 6 months after diagnosis. Intrinsic resistance to chemotherapeutics …
with a median survival of 6 months after diagnosis. Intrinsic resistance to chemotherapeutics …
[HTML][HTML] Dendrimer-based nanocomposites for the production of RNA delivery systems
CC Lim, LY Chia, PV Kumar - OpenNano, 2023 - Elsevier
A novel approach to treating cancer has been revealed to be effective cancer vaccination. It
has also been demonstrated that nucleic acid therapies such as mRNA and siRNA are very …
has also been demonstrated that nucleic acid therapies such as mRNA and siRNA are very …
Nucleic acid nanotechnology for cancer treatment
Cancer is one of the most prevalent potentially lethal diseases. With the increase in the
number of investigations into the uses of nanotechnology, many nucleic acid (NA)-based …
number of investigations into the uses of nanotechnology, many nucleic acid (NA)-based …
Tailor‐made nanomaterials for diagnosis and therapy of pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide due to
its aggressiveness and the challenge to early diagnosis and treatment. In recent decades …
its aggressiveness and the challenge to early diagnosis and treatment. In recent decades …
Current status of biomarker and targeted nanoparticle development: The precision oncology approach for pancreatic cancer therapy
Pancreatic cancer remains one of the major causes of cancer-related mortality. The majority
of pancreatic cancer patients are diagnosed at the advanced stage with unresectable and …
of pancreatic cancer patients are diagnosed at the advanced stage with unresectable and …
Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis
S Nicolai, M Pieraccioli, A Peschiaroli, G Melino… - Cell death & …, 2015 - nature.com
Neuroblastoma (NB) is the most common extracranial childhood tumor classified in five
stages (1, 2, 3, 4 and 4S), two of which (3 and 4) identify chemotherapy-resistant, highly …
stages (1, 2, 3, 4 and 4S), two of which (3 and 4) identify chemotherapy-resistant, highly …
Nonviral siRNA delivery systems for pancreatic cancer therapy
The serious drawbacks of the conventional treatment of pancreatic ductal adenocarcinoma
(PDAC) such as nonspecific toxicity and high resistance to chemo and radiation therapy …
(PDAC) such as nonspecific toxicity and high resistance to chemo and radiation therapy …