[HTML][HTML] Apelinergic system structure and function
Apelin and apela (ELABELA/ELA/Toddler) are two peptide ligands for a class A G-protein-
coupled receptor named the apelin receptor (AR/APJ/APLNR). Ligand-AR interactions have …
coupled receptor named the apelin receptor (AR/APJ/APLNR). Ligand-AR interactions have …
Thymosin α1 and its role in viral infectious diseases: the mechanism and clinical application
N Tao, X Xu, Y Ying, S Hu, Q Sun, G Lv, J Gao - Molecules, 2023 - mdpi.com
Thymosin α1 (Tα1) is an immunostimulatory peptide that is commonly used as an immune
enhancer in viral infectious diseases such as hepatitis B, hepatitis C, and acquired immune …
enhancer in viral infectious diseases such as hepatitis B, hepatitis C, and acquired immune …
Design and development of a novel peptide for treating intestinal inflammation
L Zhang, X Wei, R Zhang, JN Petitte, D Si, Z Li… - Frontiers in …, 2019 - frontiersin.org
Intestinal inflammatory disorders, such as inflammatory bowel disease (IBD), are associated
with increased pro-inflammatory cytokine secretion in the intestines. Furthermore, intestinal …
with increased pro-inflammatory cytokine secretion in the intestines. Furthermore, intestinal …
Thymosin alpha 1 and HIV-1: recent advances and future perspectives
In spite of the consistent benefits for HIV-1 infected patients undergoing antiretroviral
therapy, a complete immune reconstitution is usually not achieved. Actually, antiretroviral …
therapy, a complete immune reconstitution is usually not achieved. Actually, antiretroviral …
[HTML][HTML] The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans
NT Case, K Duah, B Larsen, CJ Wong, AC Gingras… - Cell reports, 2021 - cell.com
Evasion of killing by immune cells is crucial for fungal survival in the host. For the human
fungal pathogen Candida albicans, internalization by macrophages induces a transition …
fungal pathogen Candida albicans, internalization by macrophages induces a transition …
Thymosin α-1 in cancer therapy: Immunoregulation and potential applications
Y Wei, Y Zhang, P Li, C Yan, L Wang - International Immunopharmacology, 2023 - Elsevier
Abstract Thymosin α-1 (Tα-1) is an immunomodulating polypeptide of 28 amino acids, which
was the first peptide isolated from thymic tissue and has been widely used for the treatment …
was the first peptide isolated from thymic tissue and has been widely used for the treatment …
Thymosin alpha1-Fc modulates the immune system and down-regulates the progression of melanoma and breast cancer with a prolonged half-life
F Wang, T Yu, H Zheng, X Lao - Scientific reports, 2018 - nature.com
Abstract Thymosin alpha 1 (Tα1) is a biological response modifier that has been introduced
into markets for treating several diseases. Given the short serum half-life of Tα1 and the …
into markets for treating several diseases. Given the short serum half-life of Tα1 and the …
Serum thymosin alpha 1 levels in normal and pathological conditions
ABSTRACT Introduction: Thymosin alpha 1 (Ta1) is a natural occurring peptide hormone
that is crucial for the maintenance of the organism homeostasis. It has been chemically …
that is crucial for the maintenance of the organism homeostasis. It has been chemically …
[HTML][HTML] Apela exhibits isoform-and headgroup-dependent modulation of micelle binding, peptide conformation and dynamics
Apela (also referred to as ELABELA and toddler) is a peptide hormone that activates the
apelin receptor (AR or APJ) to regulate cardiovascular system development and function …
apelin receptor (AR or APJ) to regulate cardiovascular system development and function …
Serum thymosin α 1 levels in patients with chronic inflammatory autoimmune diseases
Summary Thymosin alpha 1 (Tα1) is a powerful modulator of immunity and inflammation.
Despite years of studies, there are a few reports evaluating serum Tα1 in health and …
Despite years of studies, there are a few reports evaluating serum Tα1 in health and …