More than two decades have elapsed since the publication of the first genome sequence of
Mycobacterium tuberculosis (Mtb) which, shortly thereafter, enabled methods to determine …

Background Diseases are one of the factors affecting human and national development in
all its ramifications. Some of the diseases that affect humans are usually difficult to manage …

Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb)
remains a threat to mankind, with over a billion of deaths in the last two centuries. Recent …

For centuries, natural products (NPs) have served as powerful therapeutics against a variety
of human ailments. Nowadays, they still represent invaluable resources for the treatment of …

Ethnopharmacological relevance Emergence of drug-resistant and multidrug-resistant
Mycobacterium tuberculosis (Mtb) strains is a major barrier to tuberculosis (TB) eradication …

The apparent predicament of the representative chemotherapy for managing respiratory
distress calls for an obligatory deliberation for identifying the pharmaceuticals that effectively …

Antibiotics are the cornerstone of modern medicine and agriculture, and rising antibiotic
resistance is one the biggest threats to global health and food security. Identifying new and …

Abstract Background Neisseria gonorrhoeae (Ng) causes the sexually transmitted disease
gonorrhoea. There are no vaccines and infections are treated principally with antibiotics …

The dormant phenotype of Mycobacterium tuberculosis that develops during infection poses
a major challenge in disease treatment, since these bacilli show tolerance to front-line …

Impaired immune responses have been observed in patients with type-2 diabetes mellitus
(T2DM), which increases susceptibility to tuberculosis infection. However, the effect of the …