[HTML][HTML] The relation between the biochemical composition of knee articular cartilage and quantitative MRI: a systematic review and meta-analysis
KS Emanuel, LJ Kellner, MJM Peters… - Osteoarthritis and …, 2022 - Elsevier
Objective Early and non-invasive detection of osteoarthritis (OA) is required to enable early
treatment and monitoring of interventions. Some of the earliest signs of OA are the change in …
treatment and monitoring of interventions. Some of the earliest signs of OA are the change in …
[HTML][HTML] Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis
Objective To assess reliability and discriminative validity of cartilage compositional magnetic
resonance imaging (MRI) in knee osteoarthritis (OA). Design The study was carried out per …
resonance imaging (MRI) in knee osteoarthritis (OA). Design The study was carried out per …
Prestructural cartilage assessment using MRI
Cartilage loss is irreversible, and to date, no effective pharmacotherapies are available to
protect or regenerate cartilage. Quantitative prestructural/compositional MR imaging …
protect or regenerate cartilage. Quantitative prestructural/compositional MR imaging …
Stem cells for cartilage repair: preclinical studies and insights in translational animal models and outcome measures
M Lo Monaco, G Merckx, J Ratajczak… - Stem Cells …, 2018 - Wiley Online Library
Due to the restricted intrinsic capacity of resident chondrocytes to regenerate the lost
cartilage postinjury, stem cell‐based therapies have been proposed as a novel therapeutic …
cartilage postinjury, stem cell‐based therapies have been proposed as a novel therapeutic …
Early knee OA definition–what do we know at this stage? An imaging perspective
While criteria for early-stage knee osteoarthritis (OA) in a primary care setting have been
proposed, the role of imaging has been limited to radiography using the standard Kellgren …
proposed, the role of imaging has been limited to radiography using the standard Kellgren …
MRI T2 and T1ρ relaxation in patients at risk for knee osteoarthritis: a systematic review and meta-analysis
Background Magnetic resonance imaging (MRI) T2 and T1ρ relaxation are increasingly
being proposed as imaging biomarkers potentially capable of detecting biochemical …
being proposed as imaging biomarkers potentially capable of detecting biochemical …
Imaging of osteoarthritis—recent research developments and future perspective
In osteoarthritis research, imaging plays an important role in clinical trials and
epidemiological observational studies. In this narrative review article, we will describe recent …
epidemiological observational studies. In this narrative review article, we will describe recent …
MRI-based T1rho and T2 cartilage compositional imaging in osteoarthritis: what have we learned and what is needed to apply it clinically and in a trial setting?
Cartilage MRI-based T1rho and T2 compositional measurements have been developed to
characterize cartilage matrix quality and diagnose cartilage damage before irreversible …
characterize cartilage matrix quality and diagnose cartilage damage before irreversible …
Cationic poly-l-lysine-encapsulated melanin nanoparticles as efficient photoacoustic agents targeting to glycosaminoglycans for the early diagnosis of articular …
Cartilage degeneration is the hallmark of osteoarthritis (OA) and its early diagnosis is
essential for effective cartilage repair. However, until now, there was still a lack of imaging …
essential for effective cartilage repair. However, until now, there was still a lack of imaging …
T2 map** of the meniscus is a biomarker for early osteoarthritis
SM Eijgenraam, FAT Bovendeert, J Verschueren… - European …, 2019 - Springer
Purpose To evaluate in vivo T 2 map** as quantitative, imaging-based biomarker for
meniscal degeneration in humans, by studying the correlation between T 2 relaxation time …
meniscal degeneration in humans, by studying the correlation between T 2 relaxation time …