Highlights•Disruption of cellular macromolecules by alcohols limits biofuel fermentations.•
Lignocellulose hydrolysis also generates chaotropic inhibitors (vanillin, phenolics …

Saccharomyces cerevisiae is one of the prominent strains in the brewing and bioethanol
industries and has been used for many industrial purposes for ages. Though the organism is …

Methanol is an attractive substrate for biological production of chemicals and fuels.
Engineering methylotrophic Escherichia coli as a platform organism for converting methanol …

Highlights•Membrane disruption limits high titer production of biofuels and
biochemicals.•Strains evolved to have high tolerance maintain optimal membrane fluidity …

Ubiquitously distributed microorganisms are natural decomposers of environmental
pollutants. However, because of continuous generation of novel recalcitrant pollutants due …

Understanding ethanol-induced stresses and responses in biofuel-producing bacteria at
systems level has significant implications in engineering more efficient biofuel producers …

Abstract 2016, was the 100 years anniversary from launching of the first industrial acetone-
butanol-ethanol (ABE) microbial production process. Despite this long period and also …

Recent studies are increasingly focusing on advanced biotechnological tools, self-adjusting
smart microorganisms, and artificial intelligent networks, to engineer microorganisms with …

Microbial cell factories provide vital platforms for the production of chemicals. Advanced
biotechnological toolboxes have been developed to enhance their efficiency. However …

Microorganisms, particularly extremophiles, have evolved multiple adaptation mechanisms
to address diverse stress conditions during survival in unique environments. Their …