[HTML][HTML] An updated review of the biomarkers of response to immune checkpoint inhibitors in Merkel cell carcinoma: Merkel cell carcinoma and immunotherapy

A Fojnica, K Ljuca, S Akhtar, Z Gatalica, S Vranic - Cancers, 2023 - mdpi.com
Simple Summary Merkel cell carcinoma (MCC) is a rare and highly aggressive type of skin
neuroendocrine cancer that frequently recurs and metastasizes within a relatively short …

Combined Merkel cell carcinoma and squamous cell carcinoma: a systematic review

E Ríos-Viñuela, F Mayo-Martínez, E Nagore… - Cancers, 2024 - mdpi.com
Simple Summary Although considerable advances have been made in the understanding of
the pathogenesis of Merkel cell carcinoma (MCC), many questions remain unanswered …

[HTML][HTML] Advancing treatment options for merkel cell carcinoma: A review of tumor-targeted therapies

HM Nammour, K Madrigal, CT Starling… - International journal of …, 2024 - mdpi.com
Although rare, Merkel cell carcinoma (MCC) is a highly aggressive and increasingly
prevalent neuroendocrine cancer of the skin. While current interventions, including surgical …

LT and SOX9 expression are associated with gene sets that distinguish Merkel cell polyomavirus (MCPyV)-positive and MCPyV-negative Merkel cell carcinoma

J Torre-Castro, M Rodríguez… - British Journal of …, 2024 - academic.oup.com
Background Merkel cell carcinoma (MCC) is an aggressive malignant neuroendocrine
tumour. There are two subsets of MCC, one related to Merkel cell polyomavirus (MCPyV) …

The role of neoadjuvant immunotherapy in the management of Merkel cell carcinoma with clinically detected regional lymph node metastasis

JH Chang, D Remulla, C Wehrle, KP Woo… - Annals of Surgical …, 2024 - Springer
Background Immunotherapy is emerging as a promising option for certain locally advanced
and metastatic cutaneous malignancies. However, the role of neoadjuvant immunotherapy …

Current status of Merkel cell carcinoma: Epidemiology, pathogenesis and prognostic factors

Z Li, W Ji, Q Hu, P Zhu, Y **, G Duan - Virology, 2024 - Elsevier
Merkel cell carcinoma (MCC) is an extremely rare cutaneous neuroendocrine cancer, with
an incidence approximately 40 times lower than that of malignant melanoma; however, its …

[HTML][HTML] Skin cancer risk is increased by somatic mutations detected noninvasively in healthy-appearing sun-exposed skin

K Kaur, R Ai, AG Perry, B Riley, EL Roberts… - Journal of Investigative …, 2024 - Elsevier
Skin cancer risk is increased by exposure to ultraviolet radiation (UVR). Because UVR
exposure accumulates over time and lighter skin is more susceptible to UVR, age and skin …

Retrospective Single-Center Case Study of Clinical Variables and the Degree of Actinic Elastosis Associated with Rare Skin Cancers

K Drexler, L Bollmann, S Karrer, M Berneburg… - …, 2024 - pmc.ncbi.nlm.nih.gov
Simple Summary While sun exposure and associated tissue changes stemming from
ultraviolet radiation are closely associated with the most common forms of skin cancer, far …

The effect of GP-2250 on cultured virus-negative Merkel cell carcinoma cells: Preliminary results

T Gambichler, B Majchrzak-Stiller, I Peters… - Journal of Cancer …, 2023 - Springer
Background Even in the novel immunotherapy era, Merkel cell carcinoma (MCC) remains
challenging in its treatment. Apart from Merkel cell polyomavirus (MCPyV) associated MCC …

Genetic and Molecular Profiling in Merkel Cell Carcinoma: Focus on MCPyV Oncoproteins and Emerging Diagnostic Techniques

H Singh, S Mohanto, A Kumar, AK Mishra… - … -Research and Practice, 2025 - Elsevier
Abstract Merkel Cell Carcinoma (MCC) is an uncommon yet highly malignant form of skin
cancer, frequently linked to the Merkel cell polyomavirus (MCPyV). This review …